Scholarly Works per year
Scholarly Works per year
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Dive into the research topics where Nancy C Horton is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Crosstalk between co-assembling filamentous enzymes
Horton, N., Aug 2024, In: BioEssays. 46, 8, 2400129.Research output: Contribution to journal › Article › peer-review
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DNA Sequence Control of Enzyme Filamentation and Activation of the SgrAI Endonuclease
Ghadirian, N., Morgan, R. D. & Horton, N. C., Feb 6 2024, In: Biochemistry. 63, 3, p. 326-338 13 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Structures, mechanisms, and kinetic advantages of the SgrAI filament forming mechanism
Horton, N. C. & Lyumkis, D., 2024, In: Critical reviews in biochemistry and molecular biology. 59, 6, p. 363-401 39 p.Research output: Contribution to journal › Review article › peer-review
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Two-metal ion mechanism of DNA cleavage by activated, filamentous SgrAI
Shan, Z., Rivero-Gamez, A., Lyumkis, D. & Horton, N. C., Aug 2024, In: Journal of Biological Chemistry. 300, 8, 107576.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Physachenolide C is a Potent, Selective BET Inhibitor
Zerio, C. J., Sivinski, J., Wijeratne, E. M. K., Xu, Y. M., Ngo, D. T., Ambrose, A. J., Villa-Celis, L., Ghadirian, N., Clarkson, M. W., Zhang, D. D., Horton, N. C., Gunatilaka, A. A. L., Fromme, R. & Chapman, E., Jan 12 2023, In: Journal of Medicinal Chemistry. 66, 1, p. 913-933 21 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations
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STRUCTURE BASED APPROACH TO ISSUES IN ZINC FINGER RECOGNITION
Horton, N. C. (PI)
Project: Research project
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BUDDING YEAST SEPTIN FILAMENTS: CONFORMATION AND KINETICS OF FILAMENT FORMATION
Horton, N. C. (PI)
Project: Research project
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Datasets
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2GIG : Alteration of sequence specificity of the type II restriction endonuclease HINCII through an indirect readout mechanism
Joshi, H. K. (Contributor), Etzkorn, C. (Contributor), Chatwell, L. (Contributor), Bitinaite, J. (Contributor) & Horton, N. C. (Contributor), RCSB-PDB, 2006
DOI: 10.2210/pdb2gig/pdb, https://www.rcsb.org/structure/2GIG
Dataset
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2GIE : HincII bound to cognate DNA GTTAAC
Bitinaite, J. (Contributor), Horton, N. C. (Contributor), Joshi, H. K. (Contributor), Etzkorn, C. (Contributor) & Chatwell, L. (Contributor), RCSB-PDB, 2006
DOI: 10.2210/pdb2gie/pdb, https://www.rcsb.org/structure/2GIE
Dataset
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3N78 : SgrAI bound to Secondary Site DNA and Mg(II)
Little, E. J. (Contributor), Dunten, P. W. (Contributor) & Horton, N. C. (Contributor), RCSB-PDB, 2010
DOI: 10.2210/pdb3n78/pdb, https://www.rcsb.org/structure/3N78
Dataset
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1KC6 : HincII Bound to Cognate DNA
Horton, N. C. (Contributor), Dorner, L. F. (Contributor) & Perona, J. J. (Contributor), RCSB-PDB, 2001
DOI: 10.2210/pdb1kc6/pdb, https://www.rcsb.org/structure/1KC6
Dataset
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2GIH : Q138F HincII bound to cognate DNA GTCGAC and Ca2+
Bitinaite, J. (Contributor), Horton, N. C. (Contributor), Joshi, H. K. (Contributor), Etzkorn, C. (Contributor) & Chatwell, L. (Contributor), RCSB-PDB, 2006
DOI: 10.2210/pdb2gih/pdb, https://www.rcsb.org/structure/2GIH
Dataset