Scholarly Works per year
Scholarly Works per year
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Dive into the research topics where Michael S Kuhns is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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The CD4 transmembrane GGXXG and juxtamembrane (C/F)CV+C motifs mediate pMHCII-specific signaling independently of CD4-LCK interactions
Lee, M. S., Tuohy, P. J., Kim, C. Y., Yost, P. P., Lichauco, K., Parrish, H. L., Van Doorslaer, K. & Kuhns, M. S., 2023, In: eLife. 12, RP88225.Research output: Contribution to journal › Article › peer-review
Open Access -
Enhancing and inhibitory motifs regulate CD4 activity
Lee, M. S., Tuohy, P. J., Kim, C. Y., Lichauco, K., Parrish, H. L., Van Doorslaer, K. & Kuhns, M. S., Jul 2022, In: eLife. 2022, 11, e79508.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
The TCR Ca Domain Regulates Responses to Self-pMHC Class II
Kim, C. Y., Parrish, H. L. & Kuhns, M. S., Nov 15 2022, In: Journal of Immunology. 209, 10, p. 2033-2041 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
A biomimetic five-module chimeric antigen receptor (5MCAR) designed to target and eliminate antigen-specific T cells
Kobayashi, S., Thelin, M. A., Parrish, H. L., Deshpande, N. R., Lee, M. S., Karimzadeh, A., Niewczas, M. A., Serwold, T. & Kuhns, M. S., Nov 17 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 46, p. 28950-28959 10 p.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
Universal Principled Review: A Community-Driven Method to Improve Peer Review
The Future Immunology Consortium, Dec 12 2019, In: Cell. 179, 7, p. 1441-1445 5 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access7 Scopus citations
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Development of Cellular Tools and Techniques to Identify Low Affinity T Cells
Kuhns, M. S. (PI)
Project: Research project
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Inducing Tolerance with 5-Module chimeric Antigen Receptor (5MCAR) T Cells
Kuhns, M. S. (PI)
Project: Research project
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Probing the mechanistic basis for T cell fate decisions (R01)
Kuhns, M. S. (PI)
Project: Research project
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Evolution-guided analysis of extracellular and intracellular mechanisms driving T cell activation
Kuhns, M. S. (PI) & Van Doorslaer, K. M. (CoPI)
Project: Research project
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Adapting 5MCAR technology for the treatment of peripheral T cell lymphoma
Kuhns, M. S. (PI)
Project: Research project
Datasets
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Crystal structure of the 226 TCR in complex with MCC-p5E/I-Ek
Newell, E. W. (Contributor), Ely, L. K. (Contributor), Kruse, A. C. (Contributor), Reay, P. A. (Contributor), Rodriguez, S. N. (Contributor), Lin, A. E. (Contributor), Kuhns, M. S. (Contributor), Garcia, K. C. (Contributor) & Davis, M. M. (Contributor), Protein Data Bank (PDB), Apr 27 2011
DOI: 10.2210/pdb3QIW/pdb, https://www.wwpdb.org/pdb?id=pdb_00003qiw
Dataset
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Crystal structure of the 2B4 TCR
Newell, E. W. (Contributor), Ely, L. K. (Contributor), Kruse, A. C. (Contributor), Reay, P. A. (Contributor), Rodriguez, S. N. (Contributor), Lin, A. E. (Contributor), Kuhns, M. S. (Contributor), Garcia, K. C. (Contributor) & Davis, M. M. (Contributor), Protein Data Bank (PDB), Apr 27 2011
DOI: 10.2210/pdb3QJF/pdb, https://www.wwpdb.org/pdb?id=pdb_00003qjf
Dataset
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Crystal structure of the 2B4 TCR in complex with MCC/I-Ek
Newell, E. W. (Contributor), Ely, L. K. (Contributor), Kruse, A. C. (Contributor), Reay, P. A. (Contributor), Rodriguez, S. N. (Contributor), Lin, A. E. (Contributor), Kuhns, M. S. (Contributor), Garcia, K. C. (Contributor) & Davis, M. M. (Contributor), Protein Data Bank (PDB), Apr 27 2011
DOI: 10.2210/pdb3QIB/pdb, https://www.wwpdb.org/pdb?id=pdb_00003qib
Dataset
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The crystal structure of the 5c.c7 TCR
Newell, E. W. (Contributor), Ely, L. K. (Contributor), Kruse, A. C. (Contributor), Reay, P. A. (Contributor), Rodriguez, S. N. (Contributor), Lin, A. E. (Contributor), Kuhns, M. S. (Contributor), Garcia, K. C. (Contributor) & Davis, M. M. (Contributor), Protein Data Bank (PDB), Apr 27 2011
DOI: 10.2210/pdb3QJH/pdb, https://www.wwpdb.org/pdb?id=pdb_00003qjh
Dataset
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Crystal structure of the 226 TCR in complex with MCC/I-Ek
Newell, E. W. (Contributor), Ely, L. K. (Contributor), Kruse, A. C. (Contributor), Reay, P. A. (Contributor), Rodriguez, S. N. (Contributor), Lin, A. E. (Contributor), Kuhns, M. S. (Contributor), Garcia, K. C. (Contributor) & Davis, M. M. (Contributor), Protein Data Bank (PDB), Apr 27 2011
DOI: 10.2210/pdb3QIU/pdb, https://www.wwpdb.org/pdb?id=pdb_00003qiu
Dataset