Scholarly Works per year
Scholarly Works per year
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Dive into the research topics where Laurence Hurley is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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A first-in-class clinical G-quadruplex-targeting drug. The bench-to-bedside translation of the fluoroquinolone QQ58 to CX-5461 (Pidnarulex)
Xu, H. & Hurley, L. H., Dec 1 2022, In: Bioorganic and Medicinal Chemistry Letters. 77, 129016.Research output: Contribution to journal › Review article › peer-review
6 Scopus citations -
Quindoline-derivatives display potent G-quadruplex-mediated antiviral activity against herpes simplex virus 1
Frasson, I., Soldà, P., Nadai, M., Tassinari, M., Scalabrin, M., Gokhale, V., Hurley, L. H. & Richter, S. N., Dec 2022, In: Antiviral Research. 208, 105432.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
The role of G-Quadruplex DNA in Paraspeckle formation in cancer
Bhatt, U., Kretzmann, A. L., Guédin, A., Ou, A., Kobelke, S., Bond, C. S., Evans, C. W., Hurley, L. H., Mergny, J. L., Iyer, K. S., Fox, A. H. & Smith, N. M., Nov 2021, In: Biochimie. 190, p. 124-131 8 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
DNA G-Quadruplex and i-Motif Structure Formation Is Interdependent in Human Cells
King, J. J., Irving, K. L., Evans, C. W., Chikhale, R. V., Becker, R., Morris, C. J., Peña Martinez, C. D., Schofield, P., Christ, D., Hurley, L. H., Waller, Z. A. E., Iyer, K. S. & Smith, N. M., Dec 9 2020, In: Journal of the American Chemical Society. 142, 49, p. 20600-20604 5 p.Research output: Contribution to journal › Article › peer-review
38 Scopus citations -
Erratum: Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex (Oncotarget (2020) 11 (1758-1776) DOI: 10.18632/oncotarget.27589)
Miranti, C. K., Moore, S., Kim, Y., Chappeta, V. R., Wu, K., De, B., Gokhale, V., Hurley, L. H. & Reyes-Reyes, E. M., Jun 30 2020, In: Oncotarget. 11, 26, p. 2586 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access
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University of Arizona Cancer Center - Cancer Center Support Grant
Bhattacharyya, A. K., Briehl, M. M., Cress, A. E., Doetschman, T. C., Ellis, N., Futscher, B. W., Garland, L. L., Hersh, E. M., Ignatenko, N., Livingston, R. B., Miesfeld, R. L., Miranti, C., Nagle, R. B., Stratton, S. P., Tsaprailis, G., Watts, G. S., Dorr, R. T., Weinstein, R. S., Hurley, L., Mash, E. A., Montfort, W. R., Warfel, N. A., Roe, D. & Miller, T. P.
Project: Research project
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Establishing a molecular system for drug targeting of transcriptional control
Project: Research project
Datasets
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In vitro activity of a G-quadruplex-stabilizing small molecule that synergizes with Navitoclax to induce cytotoxicity in acute myeloid leukemia cells
Montoya, J. J. (Creator), Turnidge, M. A. (Creator), Wai, D. H. (Creator), Patel, A. R. (Contributor), Lee, D. W. (Creator), Gokhale, V. (Creator), Hurley, L. (Creator), Arceci, R. J. (Creator), Wetmore, C. (Creator) & Azorsa, D. O. (Creator), figshare, 2019
DOI: 10.6084/m9.figshare.c.4799331.v1, https://springernature.figshare.com/collections/In_vitro_activity_of_a_G-quadruplex-stabilizing_small_molecule_that_synergizes_with_Navitoclax_to_induce_cytotoxicity_in_acute_myeloid_leukemia_cells/4799331/1
Dataset
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CCDC 858523: Experimental Crystal Structure Determination
Nichol, G. S. (Creator), Boddupally, P. V. L. (Creator), De, B. (Creator) & Hurley, L. (Creator), Cambridge Crystallographic Data Centre, 2012
DOI: 10.5517/ccxtc9c, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccxtc9c&sid=DataCite
Dataset