Scholarly Works per year
Scholarly Works per year
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Dive into the research topics where Jun Wang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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An Overview of Antivirals against Monkeypox Virus and Other Orthopoxviruses
Wang, J., Shahed-AI-Mahmud, M., Chen, A., Li, K., Tan, H. & Joyce, R., Apr 13 2023, In: Journal of Medicinal Chemistry. 66, 7, p. 4468-4490 23 p.Research output: Contribution to journal › Review article › peer-review
5 Scopus citations -
A Study of the Activity of Adamantyl Amines against Mutant Influenza A M2 Channels Identified a Polycyclic Cage Amine Triple Blocker, Explored by Molecular Dynamics Simulations and Solid-State NMR**
Stampolaki, Μ., Hoffmann, A., Tekwani, K., Georgiou, K., Tzitzoglaki, C., Ma, C., Becker, S., Schmerer, P., Döring, K., Stylianakis, I., Turcu, A. L., Wang, J., Vázquez, S., Andreas, L. B., Schmidtke, M. & Kolocouris, A., Aug 15 2023, In: ChemMedChem. 18, 16, e202300182.Research output: Contribution to journal › Article › peer-review
Open Access -
A yeast-based system to study SARS-CoV-2 Mpro structure and to identify nirmatrelvir resistant mutations
Ou, J., Lewandowski, E. M., Hu, Y., Lipinski, A. A., Aljasser, A., Colon-Ascanio, M., Morgan, R. T., Jacobs, L. M. C., Zhang, X., Bikowitz, M. J., Langlais, P. R., Tan, H., Wang, J., Chen, Y. & Choy, J. S., Aug 2023, In: PLoS pathogens. 19, 8, e1011592.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Development of the Safe and Broad-Spectrum Aldehyde and Ketoamide Mpro inhibitors Derived from the Constrained α, γ-AA Peptide Scaffold
Wang, L., Ma, C., Sacco, M. D., Xue, S., Mahmoud, M., Calcul, L., Chen, Y., Wang, J. & Cai, J., Jun 22 2023, In: Chemistry - A European Journal. 29, 35, e202300476.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Exploring diverse reactive warheads for the design of SARS-CoV-2 main protease inhibitors
Tan, B., Sacco, M., Tan, H., Li, K., Joyce, R., Zhang, X., Chen, Y. & Wang, J., Nov 5 2023, In: European journal of medicinal chemistry. 259, 115667.Research output: Contribution to journal › Article › peer-review
2 Scopus citations
Grants
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Drug target validation of the enterovirus D68 2A protease
Project: Research project
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High Throughput Screening of Inhibitors Targeting the Enterovirus A71 and D68 2A proteases
Project: Research project
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High Throughput Screening of Inhibitors Targeting the Enterovirus A71 and D68 2A Proteases
Project: Research project
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Drug Discovery Targeting the Influenza A Virus M2-S31N Proton Channel
Project: Research project
Datasets
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2LY0 : Solution NMR structure of the influenza A virus S31N mutant (19-49) in presence of drug M2WJ332
Wu, Y. (Contributor), Wang, J. (Contributor) & Degrado, W. F. (Contributor), RCSB-PDB, 2013
DOI: 10.2210/pdb2ly0/pdb, https://www.rcsb.org/structure/2LY0
Dataset
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2Q06 : Crystal structure of Influenza A Virus H5N1 Nucleoprotein
Wang, J. (Contributor), Ng, A. K. (Contributor), Zhang, H. (Contributor), Tan, K. (Contributor), Wang, J. (Contributor) & Shaw, P. (Contributor), RCSB-PDB, 2008
DOI: 10.2210/pdb2q06/pdb, https://www.rcsb.org/structure/2Q06
Dataset
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2MUV : NOE-based model of the influenza A virus M2 (19-49) bound to drug 11
Wu, Y. (Contributor), Wang, J. (Contributor) & Degrado, W. F. (Contributor), RCSB-PDB, 2014
DOI: 10.2210/pdb2muv/pdb, https://www.rcsb.org/structure/2MUV
Dataset
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CCDC 1573497: Experimental Crystal Structure Determination
Zhang, J. (Creator), Hu, Y. (Creator), Foley, C. (Creator), Wang, Y. (Creator), Musharrafieh, R. (Creator), Xu, S. (Creator), Zhang, Y. (Creator), Ma, C. (Creator), Hulme, C. (Creator) & Wang, J. (Creator), Cambridge Crystallographic Data Centre, 2018
DOI: 10.5517/ccdc.csd.cc1ptbzt, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1ptbzt&sid=DataCite
Dataset
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NOE-based model of the influenza A virus M2 (19-49) bound to drug 11
Wu, Y. (Creator), Wang, J. (Creator) & Degrado, W. F. (Contributor), Biological Magnetic Resonance Bank, Dec 22 2014
DOI: 10.13018/bmr25234, https://bmrb.io/data_library/summary/?bmrbId=25234
Dataset