Scholarly Works per year
Scholarly Works per year
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Dive into the research topics where Jun Wang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model
Tan, B., Zhang, X., Ansari, A., Jadhav, P., Tan, H., Li, K., Chopra, A., Ford, A., Chi, X., Ruiz, F. X., Arnold, E., Deng, X. & Wang, J., Mar 29 2024, In: Science. 383, 6690, p. 1434-1440 7 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
Structure and dynamics of the proton-selective histidine and the gating tryptophan in an inward rectifying hybrid influenza B and A virus M2 proton channel
Pankratova, Y., McKay, M. J., Ma, C., Tan, H., Wang, J. & Hong, M., Jul 16 2024, In: Physical Chemistry Chemical Physics. 26, 30, p. 20629-20644 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Structure-based design of SARS-CoV-2 papain-like protease inhibitors
Jadhav, P., Huang, B., Osipiuk, J., Zhang, X., Tan, H., Tesar, C., Endres, M., Jedrzejczak, R., Tan, B., Deng, X., Joachimiak, A., Cai, J. & Wang, J., Jan 15 2024, In: European journal of medicinal chemistry. 264, 116011.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
An Overview of Antivirals against Monkeypox Virus and Other Orthopoxviruses
Wang, J., Shahed-AI-Mahmud, M., Chen, A., Li, K., Tan, H. & Joyce, R., Apr 13 2023, In: Journal of Medicinal Chemistry. 66, 7, p. 4468-4490 23 p.Research output: Contribution to journal › Review article › peer-review
27 Scopus citations -
A Study of the Activity of Adamantyl Amines against Mutant Influenza A M2 Channels Identified a Polycyclic Cage Amine Triple Blocker, Explored by Molecular Dynamics Simulations and Solid-State NMR**
Stampolaki, Μ., Hoffmann, A., Tekwani, K., Georgiou, K., Tzitzoglaki, C., Ma, C., Becker, S., Schmerer, P., Döring, K., Stylianakis, I., Turcu, A. L., Wang, J., Vázquez, S., Andreas, L. B., Schmidtke, M. & Kolocouris, A., Aug 15 2023, In: ChemMedChem. 18, 16, e202300182.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations
Grants
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High Throughput Screening of Inhibitors Targeting the Enterovirus A71 and D68 2A proteases
Wang, J. (PI) & Wang, J. (CoPI)
Project: Research project
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Drug Discovery Targeting the Influenza A Virus M2-S31N Proton Channel
Wang, J. (PI)
Project: Research project
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Development of dual inhibitors targeting the viral main protease and the host cathepsin L as SARS-CoV-2 antivirals
Wang, J. (CoPI)
Project: Research project
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Drug target validation of the enterovirus D68 2A protease
Wang, J. (PI) & Wang, J. (CoPI)
Project: Research project
Datasets
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Influenza A M2 transmembrane domain bound to a spiroadamantane inhibitor
Thomaston, J. L. (Contributor), Polizzi, N. F. (Contributor), Konstantinidi, A. (Contributor), Wang, J. (Contributor), Kolocouris, A. (Contributor) & Degrado, W. F. (Contributor), Protein Data Bank (PDB), Sep 19 2018
DOI: 10.2210/pdb6BMZ/pdb, https://www.wwpdb.org/pdb?id=pdb_00006bmz
Dataset
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NOE-based model of the influenza A virus M2 (19-49) bound to drug 11
Wu, Y. (Creator), Wang, J. (Creator) & Degrado, W. F. (Contributor), Biological Magnetic Resonance Bank, Dec 22 2014
DOI: 10.13018/bmr25234, https://bmrb.io/data_library/summary/?bmrbId=25234
Dataset
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Influenza A M2 transmembrane domain bound to rimantadine
Thomaston, J. L. (Contributor), Polizzi, N. F. (Contributor), Konstantinidi, A. (Contributor), Wang, J. (Contributor), Kolocouris, A. (Contributor) & Degrado, W. F. (Contributor), Protein Data Bank (PDB), Sep 19 2018
DOI: 10.2210/pdb6BKL/pdb, https://www.wwpdb.org/pdb?id=pdb_00006bkl
Dataset
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NOE-based model of the influenza A virus M2 (19-49) bound to drug 11
Wu, Y. (Contributor), Wang, J. (Contributor) & Degrado, W. F. (Contributor), Biological Magnetic Resonance Data Bank (BMRB), Dec 22 2014
DOI: 10.13018/BMR25234, https://bmrb.io/data_library/summary/index.php?bmrbId=25234
Dataset
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CCDC 1573497: Experimental Crystal Structure Determination
Zhang, J. (Creator), Hu, Y. (Creator), Foley, C. (Creator), Wang, Y. (Creator), Musharrafieh, R. (Creator), Xu, S. (Creator), Zhang, Y. (Creator), Ma, C. (Creator), Hulme, C. (Creator) & Wang, J. (Creator), Cambridge Crystallographic Data Centre, 2018
DOI: 10.5517/ccdc.csd.cc1ptbzt, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1ptbzt&sid=DataCite
Dataset