Scholarly Works per year
Scholarly Works per year
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Dive into the research topics where Jun Wang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Identification of naturally occurring drug-resistant mutations of SARS-CoV-2 papain-like protease
Tan, H., Zhang, Q., Georgiou, K., Zhang, S., Li, K., Lambrinidis, G., Kolocouris, A., Deng, X. & Wang, J., Dec 2025, In: Nature communications. 16, 1, 4548.Research output: Contribution to journal › Article › peer-review
Open Access -
Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model
Tan, B., Zhang, X., Ansari, A., Jadhav, P., Tan, H., Li, K., Chopra, A., Ford, A., Chi, X., Ruiz, F. X., Arnold, E., Deng, X. & Wang, J., Mar 29 2024, In: Science. 383, 6690, p. 1434-1440 7 p.Research output: Contribution to journal › Article › peer-review
Open Access48 Scopus citations -
Structure and dynamics of the proton-selective histidine and the gating tryptophan in an inward rectifying hybrid influenza B and A virus M2 proton channel
Pankratova, Y., McKay, M. J., Ma, C., Tan, H., Wang, J. & Hong, M., Jul 16 2024, In: Physical Chemistry Chemical Physics. 26, 30, p. 20629-20644 16 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Structure-based design of SARS-CoV-2 papain-like protease inhibitors
Jadhav, P., Huang, B., Osipiuk, J., Zhang, X., Tan, H., Tesar, C., Endres, M., Jedrzejczak, R., Tan, B., Deng, X., Joachimiak, A., Cai, J. & Wang, J., Jan 15 2024, In: European journal of medicinal chemistry. 264, 116011.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
An Overview of Antivirals against Monkeypox Virus and Other Orthopoxviruses
Wang, J., Shahed-AI-Mahmud, M., Chen, A., Li, K., Tan, H. & Joyce, R., Apr 13 2023, In: Journal of Medicinal Chemistry. 66, 7, p. 4468-4490 23 p.Research output: Contribution to journal › Review article › peer-review
37 Scopus citations
Grants
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Drug Discovery Targeting the Influenza A Virus M2-S31N Proton Channel
Wang, J. (PI)
Project: Research project
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Drug target validation of the enterovirus D68 2A protease
Wang, J. (PI) & Wang, J. (CoPI)
Project: Research project
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Development of dual inhibitors targeting the viral main protease and the host cathepsin L as SARS-CoV-2 antivirals
Wang, J. (CoPI)
Project: Research project
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Drug Discovery Targeting the Influenza A Virus M2-S31N Proton Channel
Wang, J. (PI)
Project: Research project
Datasets
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The S31N mutant of the influenza A M2 proton channel in two distinct conformational states
Thomaston, J. L. (Contributor), Wu, Y. (Contributor), Polizzi, N. (Contributor), Liu, L. (Contributor), Wang, J. (Contributor) & Degrado, W. F. (Contributor), Protein Data Bank (PDB), Jun 26 2019
DOI: 10.2210/pdb6MJH/pdb, https://www.wwpdb.org/pdb?id=pdb_00006mjh
Dataset
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NOE-based model of the influenza A virus N31S mutant (19-49) bound to drug 11
Wu, Y. (Contributor), Canturk, B. (Contributor), Jo, H. (Contributor), Ma, C. (Contributor), Gianti, E. (Contributor), Klein, M. L. (Contributor), Pinto, L. H. (Contributor), Lamb, R. A. (Contributor), Fiorin, G. (Contributor), Wang, J. (Contributor) & Degrado, W. F. (Contributor), Protein Data Bank (PDB), Dec 24 2014
DOI: 10.2210/pdb2MUW/pdb, https://www.wwpdb.org/pdb?id=pdb_00002muw
Dataset
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Crystal structure of C. difficile SpoVD in complex with ampicillin
Sacco, M. D. (Contributor), Wang, S. (Contributor), Adapa, S. R. (Contributor), Zhang, X. (Contributor), Lewandowski, E. M. (Contributor), Gongora, M. V. (Contributor), Keramisanou, D. (Contributor), Atlas, Z. D. (Contributor), Townsend, J. A. (Contributor), Gatdula, J. R. (Contributor), Morgan, R. T. (Contributor), Hammond, L. R. (Contributor), Marty, M. T. (Contributor), Wang, J. (Contributor), Eswara, P. J. (Contributor), Gelis, I. (Contributor), Jiang, R. H. Y. (Contributor), Sun, X. (Contributor) & Chen, Y. (Contributor), Protein Data Bank (PDB), Mar 23 2022
DOI: 10.2210/pdb7RCZ/pdb, https://www.wwpdb.org/pdb?id=pdb_00007rcz
Dataset
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Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor UAWJ9-36-3
Xia, Z. (Contributor), Sacco, M. (Contributor), Hu, Y. (Contributor), Ma, C. (Contributor), Meng, X. (Contributor), Zhang, F. (Contributor), Szeto, T. (Contributor), Xiang, Y. (Contributor), Chen, Y. (Contributor) & Wang, J. (Contributor), Protein Data Bank (PDB), Mar 17 2021
DOI: 10.2210/pdb7LYI/pdb, https://www.wwpdb.org/pdb?id=pdb_00007lyi
Dataset
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CCDC 1573497: Experimental Crystal Structure Determination
Zhang, J. (Creator), Hu, Y. (Creator), Foley, C. (Creator), Wang, Y. (Creator), Musharrafieh, R. (Creator), Xu, S. (Creator), Zhang, Y. (Creator), Ma, C. (Creator), Hulme, C. (Creator) & Wang, J. (Creator), Cambridge Crystallographic Data Centre, 2018
DOI: 10.5517/ccdc.csd.cc1ptbzt, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1ptbzt&sid=DataCite
Dataset