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Dive into the research topics where Hesham Sadek is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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ETV2–ECSCR–mTOR pathways regulate reprogramming to the endothelial lineage
Choi, Y. G., Das, S., Larson, T. A., Le, A. Q., Nagarajan, U., Sadek, H. A., Zhang, J., Garry, M. G. & Garry, D. J., Mar 1 2026, In: Stem Cells. 44, 3, sxaf075.Research output: Contribution to journal › Article › peer-review
Open Access -
Left Ventricular Assist Device–Mediated Unloading and Circulatory Support as a Potential Regenerative Strategy in Advanced Heart Failure
BERGMANN, O., TSELIOU, E., SADEK, H. & DRAKOS, S. G., 2026, (Accepted/In press) In: Journal of cardiac failure.Research output: Contribution to journal › Article › peer-review
Open Access -
A Latent Cardiomyocyte Regeneration Potential in Human Heart Disease
Derks, W., Rode, J., Collin, S., Rost, F., Heinke, P., Hariharan, A., Pickel, L., Simonova, I., Lázár, E., Graham, E., Jashari, R., Andrä, M., Jeppsson, A., Salehpour, M., Alkass, K., Druid, H., Kyriakopoulos, C. P., Taleb, I., Shankar, T. S. & Selzman, C. H. & 6 others, , Jan 21 2025, In: Circulation. 151, 3, p. 245-256 12 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Link opens in a new tab Scopus citations -
An FDA-approved drug structurally and phenotypically corrects the K210del mutation in genetic cardiomyopathy models
Wang, P., Ahmed, M. S., Nguyen, N. U. N., Menendez-Montes, I., Hsu, C. C., Farag, A. B., Thet, S., Lam, N. T., Wansapura, J. P., Crossley, E., Ma, N., Zhao, S. R., Zhang, T., Morimoto, S., Singh, R., Elhelaly, W., Tassin, T. C., Cardoso, A. C., Williams, N. S. & Pointer, H. L. & 6 others, , Feb 17 2025, In: Journal of Clinical Investigation. 135, 4, e174081.Research output: Contribution to journal › Article › peer-review
Open Access -
Cardiotropic AAV gene therapy for heart failure: a phase 1 trial
Henry, T. D., Chung, E. S., Alvisi, M., Sethna, F., Murray, D. R., Traverse, J. H., Roessig, L., Roberts, L., Reddy, S., Chen, Y., Ozkan, T. G., Webb, S., Mittal, M., Ervin, L., Sadek, H., Mikhail, S., Haghighi, K., Jiang, C., Samulski, R. J. & Kranias, E. G. & 2 others, , Nov 2025, In: Nature Medicine. 31, 11, p. 3845-3852 8 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Link opens in a new tab Scopus citations
Grants
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Deciphering the Neonatal Cardiac Regenerative Potential and Regulators in Large Animals
Sadek, H. (CoPI)
Project: Research project
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Supply and Demand: Oxygen and Workload Regulate Cardiomyocyte Proliferation
Sadek, H. (PI)
Project: Research project
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T-Cell-Mediated Inflammatory Response in Neonatal Heart Regeneration
Sadek, H. (PI)
Project: Research project
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A Novel RAD51-BRCA2 Complex Stabilizing Drug: A Medical Countermeasure for Mitigating Accidental Radiation Exposure
Sadek, H. (CoPI)
Project: Research project
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Regulation of Cardiomyocyte Turnover in the Adult Mammalian Heart
Sadek, H. (PI)
Project: Research project