Scholarly Works per year
Scholarly Works per year
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Dive into the research topics where Hendrikus L Granzier is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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An ovary-intact postmenopausal HFpEF mouse model; menopause is more than just estrogen deficiency
Methawasin, M., Strom, J., Marino, V. A., Gohlke, J., Muldoon, J., Herrick, S. R., van der Piji, R., Konhilas, J. P. & Granzier, H., Apr 2025, In: American Journal of Physiology - Heart and Circulatory Physiology. 328, 4, p. H719-H733Research output: Contribution to journal › Article › peer-review
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Differential sex-dependent susceptibility to diastolic dysfunction and arrhythmia in cardiomyocytes from obese diabetic heart failure with preserved ejection fraction model
Hernandez, J. M., Shen, E. Y., Ko, C. Y., Hourani, Z., Spencer, E. R., Smoliarchuk, D., Bossuyt, J., Granzier, H., Bers, D. M. & Hegyi, B., Jan 1 2025, In: Cardiovascular research. 121, 2, p. 254-266 13 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Discovery of Titin and Its Role in Heart Function and Disease
Granzier, H. L. & Labeit, S., Jan 3 2025, In: Circulation research. 136, 1, p. 135-157 23 p.Research output: Contribution to journal › Review article › peer-review
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Generation of a novel mouse model of nemaline myopathy due to recurrent NEB exon 55 deletion
Coulson, Z., Kolb, J., Sabha, N., Karimi, E., Hourani, Z., Ottenheijm, C., Granzier, H. & Dowling, J. J., Dec 2025, In: Skeletal muscle. 15, 1, 8.Research output: Contribution to journal › Article › peer-review
Open Access -
Importance of N2BA Titin in Maintaining Cardiac Homeostasis and Its Role in Dilated Cardiomyopathy
Van Der Pijl, R., Nusayr, E., Strom, J., Slater, R., Gohlke, J., Hourani, Z., Saripalli, C., Kolb, J., Hermanson, K., Brynnel, O., Smith, J. E., Labeit, S., Methawasin, M. & Granzier, H., Mar 1 2025, In: Circulation: Heart Failure. 18, 3, p. 311-324 14 p., e012083.Research output: Contribution to journal › Article › peer-review
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Titin in Skeletal Muscle Health and Disease
Granzier, H. L. (PI) & Granzier, H. L. (CoPI)
Project: Research project
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Roles of Nebulin in Structure and Function of Striated Muscle
Granzier, H. L. (PI)
Project: Research project
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Datasets
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Phosphodiesterase 9a Inhibition in Mouse Models of Diastolic Dysfunction
Strom, J. (Creator), Borkowski, T. (Creator), Hourani, Z. (Creator), Smith, J. E. (Creator), Granzier, H. (Creator) & Methawasin, M. (Creator), University of Arizona Research Data Repository, 2023
DOI: 10.25422/azu.data.22122197.v1, https://arizona.figshare.com/articles/dataset/Phosphodiesterase_9a_Inhibition_in_Mouse_Models_of_Diastolic_Dysfunction/22122197/1
Dataset
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Supplementary material from "Exploration of pathomechanisms triggered by a single-nucleotide polymorphism in titin's I-band: the cardiomyopathy-linked mutation T2580I"
Bogomolovas, J. (Creator), Fleming, J. R. (Creator), Anderson, B. R. (Creator), Williams, R. (Creator), Lange, S. (Creator), Simon, B. (Creator), Khan, M. M. (Contributor), Rudolf, R. (Creator), Franke, B. (Creator), Bullard, B. (Creator), Rigden, D. J. (Creator), Granzier, H. (Creator), Labeit, S. (Creator) & Mayans, O. (Creator), figshare, 2016
DOI: 10.6084/m9.figshare.c.3469731, https://figshare.com/collections/Supplementary_material_from_Exploration_of_pathomechanisms_triggered_by_a_single-nucleotide_polymorphism_in_titin_s_I-band_the_cardiomyopathy-linked_mutation_T2580I_/3469731
Dataset
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Crystal structure of I9-I11 tandem from titin (P1)
Bogomolovas, J. (Contributor), Fleming, J. R. (Contributor), Anderson, B. R. (Contributor), Williams, R. (Contributor), Lange, S. (Contributor), Simon, B. (Contributor), Khan, M. M. (Contributor), Rudolf, R. (Contributor), Franke, B. (Contributor), Bullard, B. (Contributor), Rigden, D. J. (Contributor), Granzier, H. (Contributor), Labeit, S. (Contributor) & Mayans, O. (Contributor), Protein Data Bank (PDB), Sep 14 2016
DOI: 10.2210/pdb5JDE/pdb, https://www.wwpdb.org/pdb?id=pdb_00005jde
Dataset
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NEB mutations disrupt the super-relaxed state of myosin and remodel the muscle metabolic proteome in nemaline myopathy
Kontrogianni-Konstantopoulos, A. (Creator), Kolb, J. S. (Creator), Palmio, J. (Creator), Beck, T. N. (Creator), Moggio, M. G. (Creator), Witting, N. (Creator), Voermans, N. C. (Creator), Zanoteli, E. (Creator), Fiorillo, C. (Creator), Auranen, M. P. (Creator), Wallgren-Pettersson, C. (Creator), Huovinen, S. P. (Creator), Ranu, N. (Creator), Granzier, H. L. M. (Creator), Ochala, J. (Creator), Mariano, J. M. (Creator) & Vissing, J. (Creator), figshare, 2024
DOI: 10.6084/m9.figshare.c.6582904.v1, https://springernature.figshare.com/collections/NEB_mutations_disrupt_the_super-relaxed_state_of_myosin_and_remodel_the_muscle_metabolic_proteome_in_nemaline_myopathy/6582904/1
Dataset
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Expressing a Z-disk nebulin fragment in nebulin-deficient mouse muscle: effects on muscle structure and function
Li, F. (Creator), Kolb, J. (Creator), Crudele, J. (Creator), Hourani, Z. (Creator), Smith, J. E. (Creator), Chamberlain, J. S. (Creator), Granzier, H. (Creator), Chamberlain, J. (Creator) & Granzier, H. (Creator), figshare, 2020
DOI: 10.6084/m9.figshare.c.4834359, https://springernature.figshare.com/collections/Expressing_a_Z-disk_nebulin_fragment_in_nebulin-deficient_mouse_muscle_effects_on_muscle_structure_and_function/4834359
Dataset