Scholarly Works per year
Scholarly Works per year
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Dive into the research topics where Gregory Thatcher is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Inhibition of ACAT as a Therapeutic Target for Alzheimer’s Disease Is Independent of ApoE4 Lipidation
Valencia-Olvera, A. C., Balu, D., Faulk, N., Amiridis, A., Wang, Y., Pham, C., Avila-Munoz, E., York, J. M., Thatcher, G. R. J. & LaDu, M. J., 2023, (Accepted/In press) In: Neurotherapeutics.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Iodocyclization of S–(homo)propargyl dithiocarbamates: Regiospecific synthesis of 2-imino(iminium)-1, 3-dithiolanes/dithianes/dithiepanes
Soleymani, F., Ziyaei Halimehjani, A., Asar, F. J. & Thatcher, G. R. J., Sep 19 2023, In: Tetrahedron Letters. 128, 154702.Research output: Contribution to journal › Article › peer-review
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Mechanism of Allosteric Modulation of Nicotinamide Phosphoribosyltransferase to Elevate Cellular NAD+
Ratia, K. M., Shen, Z., Gordon-Blake, J., Lee, H., Laham, M. S., Krider, I. S., Christie, N., Ackerman-Berrier, M., Penton, C., Knowles, N. G., Musku, S. R., Fu, J., Velma, G. R., Xiong, R. & Thatcher, G. R. J., Feb 21 2023, In: Biochemistry. 62, 4, p. 923-933 11 p.Research output: Contribution to journal › Article › peer-review
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TrkA expression directs the anti-neoplastic activity of MLK3 inhibitors in triple-negative breast cancer
Nair, R. S., Kumar, S., Das, S., Singh, S. K., Srivastava, P., Sondarva, G., Rao, A., Sinha, S. C., Xiong, R., Bloem, L., Hoskins, K., Thatcher, G. R. J., Rana, B. & Rana, A., Mar 30 2023, In: Oncogene. 42, 14, p. 1132-1143 12 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Design of SARS-CoV-2 PLpro Inhibitors for COVID-19 Antiviral Therapy Leveraging Binding Cooperativity
Shen, Z., Ratia, K., Cooper, L., Kong, D., Lee, H., Kwon, Y., Li, Y., Alqarni, S., Huang, F., Dubrovskyi, O., Rong, L., Thatcher, G. R. J. & Xiong, R., Feb 24 2022, In: Journal of Medicinal Chemistry. 65, 4, p. 2940-2955 16 p.Research output: Contribution to journal › Article › peer-review
65 Scopus citations
Grants
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Nomethiazoles harnessing GABA and NO mimetic activity for Alzheimer's therapy
Project: Research project
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Harnessing GABA and NO mimetic activity for Alzheimer's therapy
Project: Research project
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Discovery of PPI inhibitors for the FAK FAT domain
Project: Research project
Datasets
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CCDC 2156558: Experimental Crystal Structure Determination
Alqarni, S. (Contributor), Cooper, L. (Contributor), Galvan Achi, J. (Contributor), Bott, R. (Contributor), Sali, V. K. (Contributor), Brown, A. (Contributor), Santarsiero, B. D. (Contributor), Krunic, A. (Contributor), Manicassamy, B. (Contributor), Peet, N. P. (Contributor), Zhang, P. (Contributor), Thatcher, G. (Contributor), Gaisina, I. N. (Contributor), Rong, L. (Contributor), Moore, T. W. (Contributor) & Achi, J. G. (Contributor), Cambridge Crystallographic Data Centre, 2022
DOI: 10.5517/ccdc.csd.cc2bd2d7, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc2bd2d7&sid=DataCite
Dataset