Scholarly Works per year
Scholarly Works per year
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Dive into the research topics where Frank Porreca is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Advancing understanding of migraine pathophysiology and therapy by consideration of patient sex
Porreca, F., Navratilova, E. & Dodick, D. W., May 2025, In: Cephalalgia. 45, 5, 03331024251339466.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Anti-CV2/CRMP5 autoantibodies as drivers of sensory neuron excitability and pain in rats
Martin, L., Stratton, H. J., Salih, L. Y., Dumaire, N. L. A., Gomez, K., Do, L. D., Loya-Lopez, S., Tang, C., Calderon-Rivera, A., Ran, D., Nunna, V., Bellampalli, S. S., François-Moutal, L., Luo, S., Porreca, F., Ibrahim, M., Rogemond, V., Honnorat, J., Khanna, R. & Moutal, A., Dec 2025, In: Nature communications. 16, 1, 7311.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
A prolactin-targeting antibody to prevent stress-induced peripheral nociceptor sensitization and female postoperative pain
Stratton, H. J., Dolatyari, M., Kopruszinski, C., Ghetti, A., Maciuba, S., Bowden, G., Rivière, P., Barber, K., Dodick, D. W., Edorh, E., Dumaire, N., Moutal, A., Navratilova, E. & Porreca, F., May 20 2025, In: Proceedings of the National Academy of Sciences of the United States of America. 122, 20, e2501229122.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Chronification of migraine sensitizes to CGRP in male and female mice
Guzman, G., Kopruszinski, C. M., Barber, K. R., Lillo Vizin, R. C., Dodick, D. W., Navratilova, E. & Porreca, F., Feb 2025, In: Cephalalgia. 45, 2Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Descending facilitation from rostral ventromedial medulla mu opioid receptor-expressing neurons is necessary for maintenance of sensory and affective dimensions of chronic neuropathic pain
Dogrul, B. N., Machado Kopruszinski, C., Dolatyari Eslami, M., Watanabe, M., Luo, S., Moreira De Souza, L. H., Vizin, R. L., Yue, X., Palmiter, R. D., Navratilova, E. & Porreca, F., Jan 1 2025, In: Pain. 166, 1, p. 153-159 7 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations
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Long-Acting Peripherally-Restricted Peptidic Kappa Opioid Receptor Agonists for Pain
Porreca, F. (CoPI)
Project: Research project
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New Modalities for the Treatment of Pain and Drug Abuse
Hruby, V. J. (CoPI), Hruby, V. J. (PI), Porreca, F. (PI) & Vanderah, T. W. (PI)
Project: Research project
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New Modalities for the Treatment of Pain and Drug Abuse-Administrative Core
Porreca, F. (PI)
Project: Research project
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Stress-induced descending facilitation from amygdala kappa opioid receptors in functional pain
Porreca, F. (PI)
Project: Research project
Datasets
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A novel, injury-free rodent model of vulnerability for assessment of acute and preventive therapies reveals temporal contributions of CGRP-receptor activation in migraine-like pain
Kopruszinski, C. M. (Creator), Navratilova, E. (Creator), Swiokla, J. (Creator), Dodick, D. W. (Creator), Chessell, I. P. (Creator) & Porreca, F. (Creator), SAGE Journals, 2020
DOI: 10.25384/sage.c.5134864, https://sage.figshare.com/collections/A_novel_injury-free_rodent_model_of_vulnerability_for_assessment_of_acute_and_preventive_therapies_reveals_temporal_contributions_of_CGRP-receptor_activation_in_migraine-like_pain/5134864
Dataset
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A novel, injury-free rodent model of vulnerability for assessment of acute and preventive therapies reveals temporal contributions of CGRP-receptor activation in migraine-like pain
Kopruszinski, C. M. (Creator), Navratilova, E. (Creator), Swiokla, J. (Creator), Dodick, D. W. (Creator), Chessell, I. P. (Creator) & Porreca, F. (Creator), SAGE Journals, 2020
DOI: 10.25384/sage.c.5134864.v1, https://sage.figshare.com/collections/A_novel_injury-free_rodent_model_of_vulnerability_for_assessment_of_acute_and_preventive_therapies_reveals_temporal_contributions_of_CGRP-receptor_activation_in_migraine-like_pain/5134864/1
Dataset
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Characterization and preclinical evaluation of a protease activated receptor 2 (PAR2) monoclonal antibody as a preventive therapy for migraine
Kopruszinski, C. M. (Creator), Thornton, P. (Creator), Arnold, J. (Creator), Newton, P. (Creator), Lowne, D. (Creator), Navratilova, E. (Creator), Swiokla, J. (Creator), Dodick, D. W. (Creator), Dobson, C. (Creator), Gurrell, I. (Creator), Chessell, I. P. (Creator) & Porreca, F. (Creator), SAGE Journals, 2020
DOI: 10.25384/sage.c.5195392.v1, https://sage.figshare.com/collections/Characterization_and_preclinical_evaluation_of_a_protease_activated_receptor_2_PAR2_monoclonal_antibody_as_a_preventive_therapy_for_migraine/5195392/1
Dataset
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Characterization and preclinical evaluation of a protease activated receptor 2 (PAR2) monoclonal antibody as a preventive therapy for migraine
Kopruszinski, C. M. (Creator), Thornton, P. (Creator), Arnold, J. (Creator), Newton, P. (Creator), Lowne, D. (Creator), Navratilova, E. (Creator), Swiokla, J. (Creator), Dodick, D. W. (Creator), Dobson, C. (Creator), Gurrell, I. (Creator), Chessell, I. P. (Creator) & Porreca, F. (Creator), SAGE Journals, 2020
DOI: 10.25384/sage.c.5195392.v1, https://sage.figshare.com/collections/Characterization_and_preclinical_evaluation_of_a_protease_activated_receptor_2_PAR2_monoclonal_antibody_as_a_preventive_therapy_for_migraine/5195392/1
Dataset
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Characterization and preclinical evaluation of a protease activated receptor 2 (PAR2) monoclonal antibody as a preventive therapy for migraine
Kopruszinski, C. M. (Creator), Thornton, P. (Creator), Arnold, J. (Creator), Newton, P. (Creator), Lowne, D. (Creator), Navratilova, E. (Creator), Swiokla, J. (Creator), Dodick, D. W. (Creator), Dobson, C. (Creator), Gurrell, I. (Creator), Chessell, I. P. (Creator) & Porreca, F. (Creator), SAGE Journals, 2020
DOI: 10.25384/sage.c.5195392, https://sage.figshare.com/collections/Characterization_and_preclinical_evaluation_of_a_protease_activated_receptor_2_PAR2_monoclonal_antibody_as_a_preventive_therapy_for_migraine/5195392
Dataset