Scholarly Works per year
Scholarly Works per year
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Dive into the research topics where Daniela C Zarnescu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Modelling TDP-43 proteinopathy in Drosophila uncovers shared and neuron-specific targets across ALS and FTD relevant circuits
Godfrey, R. K., Alsop, E., Bjork, R. T., Chauhan, B. S., Ruvalcaba, H. C., Antone, J., Gittings, L. M., Michael, A. F., Williams, C., Hala’ufia, G., Blythe, A. D., Hall, M., Sattler, R., Van Keuren-Jensen, K. & Zarnescu, D. C., Dec 2023, In: Acta neuropathologica communications. 11, 1, 168.Research output: Contribution to journal › Article › peer-review
Open Access -
PIKFYVE inhibition mitigates disease in models of diverse forms of ALS
Hung, S. T., Linares, G. R., Chang, W. H., Eoh, Y., Krishnan, G., Mendonca, S., Hong, S., Shi, Y., Santana, M., Kueth, C., Macklin-Isquierdo, S., Perry, S., Duhaime, S., Maios, C., Chang, J., Perez, J., Couto, A., Lai, J., Li, Y. & Alworth, S. V. & 8 others, , Feb 16 2023, In: Cell. 186, 4, p. 786-802.e28Research output: Contribution to journal › Article › peer-review
Open Access37 Scopus citations -
Dysregulation of Translation in TDP-43 Proteinopathies: Deficits in the RNA Supply Chain and Local Protein Production
Bjork, R. T., Mortimore, N. P., Loganathan, S. & Zarnescu, D. C., Mar 7 2022, In: Frontiers in Neuroscience. 16, 840357.Research output: Contribution to journal › Review article › peer-review
Open Access19 Scopus citations -
TDP-43 Proteinopathy Causes Broad Metabolic Alterations including TCA Cycle Intermediates and Dopamine Levels in Drosophila Models of ALS
Loganathan, S., Wilson, B. A., Carey, S. B., Manzo, E., Joardar, A., Ugur, B. & Zarnescu, D. C., Feb 2022, In: Metabolites. 12, 2, 101.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Author Correction: Mutations disrupting neuritogenesis genes confer risk for cerebral palsy (Nature Genetics, (2020), 52, 10, (1046-1056), 10.1038/s41588-020-0695-1)
Jin, S. C., Lewis, S. A., Bakhtiari, S., Zeng, X., Sierant, M. C., Shetty, S., Nordlie, S. M., Elie, A., Corbett, M. A., Norton, B. Y., van Eyk, C. L., Haider, S., Guida, B. S., Magee, H., Liu, J., Pastore, S., Vincent, J. B., Brunstrom-Hernandez, J., Papavasileiou, A. & Fahey, M. C. & 57 others, , Mar 2021, In: Nature Genetics. 53, 3, p. 412 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access2 Scopus citations
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Translation dysregulation in neurodegeneration
Zarnescu, D. C. (PI) & Zarnescu, D. C. (CoPI)
Project: Research project
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Mechanisms underlying the protective role of glycolysis in ALS
Zarnescu, D. C. (PI)
Project: Research project
Datasets
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Additional file 3 of TDP-43 proteinopathy alters the ribosome association of multiple mRNAs including the glypican Dally-like protein (Dlp)/GPC6
Lehmkuhl, E. M. (Creator), Loganathan, S. (Contributor), Alsop, E. (Creator), Blythe, A. D. (Creator), Kovalik, T. (Creator), Mortimore, N. P. (Creator), Barrameda, D. (Creator), Kueth, C. (Contributor), Eck, R. J. (Creator), Siddegowda, B. B. (Creator), Joardar, A. (Contributor), Ball, H. (Creator), Macias, M. E. (Creator), Bowser, R. (Creator), Van Keuren-Jensen, K. (Contributor), Zarnescu, D. C. (Creator) & Keuren-Jensen, K. V. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.14299509, https://springernature.figshare.com/articles/dataset/Additional_file_3_of_TDP-43_proteinopathy_alters_the_ribosome_association_of_multiple_mRNAs_including_the_glypican_Dally-like_protein_Dlp_GPC6/14299509
Dataset
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Additional file 1 of TDP-43 proteinopathy alters the ribosome association of multiple mRNAs including the glypican Dally-like protein (Dlp)/GPC6
Lehmkuhl, E. M. (Creator), Loganathan, S. (Contributor), Alsop, E. (Creator), Blythe, A. D. (Creator), Kovalik, T. (Creator), Mortimore, N. P. (Creator), Barrameda, D. (Creator), Kueth, C. (Contributor), Eck, R. J. (Creator), Siddegowda, B. B. (Creator), Joardar, A. (Contributor), Ball, H. (Creator), Macias, M. E. (Creator), Bowser, R. (Creator), Van Keuren-Jensen, K. (Contributor) & Zarnescu, D. C. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.14299503, https://springernature.figshare.com/articles/dataset/Additional_file_1_of_TDP-43_proteinopathy_alters_the_ribosome_association_of_multiple_mRNAs_including_the_glypican_Dally-like_protein_Dlp_GPC6/14299503
Dataset
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Additional file 2 of TDP-43 proteinopathy alters the ribosome association of multiple mRNAs including the glypican Dally-like protein (Dlp)/GPC6
Lehmkuhl, E. M. (Creator), Loganathan, S. (Contributor), Alsop, E. (Creator), Blythe, A. D. (Creator), Kovalik, T. (Creator), Mortimore, N. P. (Creator), Barrameda, D. (Creator), Kueth, C. (Contributor), Eck, R. J. (Creator), Siddegowda, B. B. (Creator), Joardar, A. (Contributor), Ball, H. (Creator), Macias, M. E. (Creator), Bowser, R. (Creator), Van Keuren-Jensen, K. (Contributor), Zarnescu, D. C. (Creator) & Keuren-Jensen, K. V. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.14299506, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_TDP-43_proteinopathy_alters_the_ribosome_association_of_multiple_mRNAs_including_the_glypican_Dally-like_protein_Dlp_GPC6/14299506
Dataset
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Additional file 4 of TDP-43 proteinopathy alters the ribosome association of multiple mRNAs including the glypican Dally-like protein (Dlp)/GPC6
Lehmkuhl, E. M. (Creator), Loganathan, S. (Contributor), Alsop, E. (Creator), Blythe, A. D. (Creator), Kovalik, T. (Creator), Mortimore, N. P. (Creator), Barrameda, D. (Creator), Kueth, C. (Contributor), Eck, R. J. (Creator), Siddegowda, B. B. (Creator), Joardar, A. (Contributor), Ball, H. (Creator), Macias, M. E. (Creator), Bowser, R. (Creator), Van Keuren-Jensen, K. (Contributor) & Zarnescu, D. C. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.14299512.v1, https://springernature.figshare.com/articles/dataset/Additional_file_4_of_TDP-43_proteinopathy_alters_the_ribosome_association_of_multiple_mRNAs_including_the_glypican_Dally-like_protein_Dlp_GPC6/14299512/1
Dataset
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Additional file 4 of TDP-43 proteinopathy alters the ribosome association of multiple mRNAs including the glypican Dally-like protein (Dlp)/GPC6
Lehmkuhl, E. M. (Creator), Loganathan, S. (Contributor), Alsop, E. (Creator), Blythe, A. D. (Creator), Kovalik, T. (Creator), Mortimore, N. P. (Creator), Barrameda, D. (Creator), Kueth, C. (Contributor), Eck, R. J. (Creator), Siddegowda, B. B. (Creator), Joardar, A. (Contributor), Ball, H. (Creator), Macias, M. E. (Creator), Bowser, R. (Creator), Van Keuren-Jensen, K. (Contributor) & Zarnescu, D. C. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.14299512, https://springernature.figshare.com/articles/dataset/Additional_file_4_of_TDP-43_proteinopathy_alters_the_ribosome_association_of_multiple_mRNAs_including_the_glypican_Dally-like_protein_Dlp_GPC6/14299512
Dataset