Scholarly Works per year
Scholarly Works per year
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Dive into the research topics where Christopher Hulme is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Barettin, a Nonopioid, Nonhallucinogenic Marine Natural Product with Antihyperalgesic Properties Mediated by 5HT2A Inverse Agonism
Seekins, C. A., Okine, M., Forrest, E. G., Chavez, T., Stump, A., Kaleeswaran, V., Carr, J. E., Hulme, C., Cardenas, P., Vanderah, T. W., Streicher, J. M. & Cartmell, C., Apr 24 2026, In: Journal Of Natural Products. 89, 4, p. 1298-1308 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Deuterated reagents in multicomponent reactions to afford deuterium-labeled products
Schofield, K., Maddern, S., Zhang, Y., Mastin, G. E., Knight, R., Wang, W., Galligan, J. & Hulme, C., 2024, In: Beilstein Journal of Organic Chemistry. 20, p. 2270-2279 10 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Scopus citations -
Discovery and Functional Characterization of a Potent, Selective, and Metabolically Stable PROTAC of the Protein Kinases DYRK1A and DYRK1B
Wilms, G., Schofield, K., Maddern, S., Foley, C., Shaw, Y., Smith, B., Basantes, L. E., Schwandt, K., Babendreyer, A., Chavez, T., McKee, N., Gokhale, V., Kallabis, S., Meissner, F., Rokey, S. N., Dunckley, T., Montfort, W. R., Becker, W. & Hulme, C., Oct 10 2024, In: Journal of Medicinal Chemistry. 67, 19, p. 17259-17289 31 p.Research output: Contribution to journal › Article › peer-review
10 Link opens in a new tab Scopus citations -
DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner
Strine, M. S., Cai, W. L., Wei, J., Alfajaro, M. M., Filler, R. B., Biering, S. B., Sarnik, S., Chow, R. D., Patil, A., Cervantes, K. S., Collings, C. K., DeWeirdt, P. C., Hanna, R. E., Schofield, K., Hulme, C., Konermann, S., Doench, J. G., Hsu, P. D., Kadoch, C. & Yan, Q. & 1 others, , Jun 2023, In: PLoS biology. 21, 6 June, e3002097.Research output: Contribution to journal › Article › peer-review
Open Access24 Link opens in a new tab Scopus citations -
The full spectrum tuning of fluorescent molecules via a one-pot multicomponent reaction
Bedard, N., Coen, A. G., Pekarske, S., Sennett, A., Davis, G. J., Chavez, T., Lichtenberger, D. L. & Hulme, C., Oct 25 2023, In: Tetrahedron Letters. 130, 154748.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Scopus citations
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Commercialization of Selective Dyrk1a Inhibitors for Down Syndrome
Hulme, C. (CoPI)
Project: Research project
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DYRK1A Inhibition as a Novel Treatment Approach for Alzheimer's Disease
Hulme, C. (CoPI) & Hulme, C. (PI)
Project: Research project
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Expeditious, biologically driven Pilot Libraries for File Enhancement
Hulme, C. (PI)
Project: Research project
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The Southwest Comprehensive Center for Drug Discovery and Development
Hulme, C. (CoPI)
Project: Research project
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Commercialization of Selective Dyrk1a Inhibitors for Down Syndrome
Hulme, C. (CoPI)
Project: Research project
Datasets
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CCDC 1445358: Experimental Crystal Structure Determination
Martinez-Ariza, G. (Creator), Mehari, B. T. (Creator), Pinho, L. A. G. (Creator), Foley, C. (Creator), Day, K. (Creator), Jewett, J. C. (Creator) & Hulme, C. (Creator), Cambridge Crystallographic Data Centre, 2017
DOI: 10.5517/ccdc.csd.cc1kj0gk, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1kj0gk&sid=DataCite
Dataset
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CCDC 985092: Experimental Crystal Structure Determination
Martinez-Ariza, G. (Creator), Ayaz, M. (Creator) & Hulme, C. (Creator), Cambridge Crystallographic Data Centre, 2014
DOI: 10.5517/cc12225d, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc12225d&sid=DataCite
Dataset
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CCDC 1027552: Experimental Crystal Structure Determination
Xu, Z. (Creator), Martinez-Ariza, G. (Creator), Cappelli, A. P. (Creator), Roberts, S. A. (Creator) & Hulme, C. (Creator), Cambridge Crystallographic Data Centre, 2015
DOI: 10.5517/cc13h7vp, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc13h7vp&sid=DataCite
Dataset
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CCDC 941765: Experimental Crystal Structure Determination
Xu, Z. (Creator), Shaw, A. Y. (Creator), Dietrich, J. (Creator), Cappelli, A. P. (Creator), Nichol, G. (Creator) & Hulme, C. (Creator), Cambridge Crystallographic Data Centre, 2013
DOI: 10.5517/cc10lzj3, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc10lzj3&sid=DataCite
Dataset
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CCDC 1027637: Experimental Crystal Structure Determination
Xu, Z. (Creator), Martinez-Ariza, G. (Creator), Cappelli, A. P. (Creator), Roberts, S. A. (Creator) & Hulme, C. (Creator), Cambridge Crystallographic Data Centre, 2015
DOI: 10.5517/cc13hblj, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc13hblj&sid=DataCite
Dataset