Scholarly Works per year
Scholarly Works per year
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Dive into the research topics where Christopher Hulme is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Barettin, a Nonopioid, Nonhallucinogenic Marine Natural Product with Antihyperalgesic Properties Mediated by 5HT2A Inverse Agonism
Seekins, C. A., Okine, M., Forrest, E. G., Chavez, T., Stump, A., Kaleeswaran, V., Carr, J. E., Hulme, C., Cardenas, P., Vanderah, T. W., Streicher, J. M. & Cartmell, C., Apr 24 2026, In: Journal Of Natural Products. 89, 4, p. 1298-1308 11 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Barettin Suppresses Pancreatic Ductal Adenocarcinoma Proliferation via Topoisomerase IIα Inhibition
Seekins, C. A., Archuleta, M. R., Evans, A. E., Podgorski, J., Carr, J. E., Kaleeswaran, V., Nguyen, K. B., Flowers, M. E., Hulme, C., Vanderah, T. W., Cárdenas, P., Streicher, J. M., Lee, N. Y. & Cartmell, C., Jun 2026, In: Marine Drugs. 24, 6, 201.Research output: Contribution to journal › Article › peer-review
Open Access -
Deuterated reagents in multicomponent reactions to afford deuterium-labeled products
Schofield, K., Maddern, S., Zhang, Y., Mastin, G. E., Knight, R., Wang, W., Galligan, J. & Hulme, C., 2024, In: Beilstein Journal of Organic Chemistry. 20, p. 2270-2279 10 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Scopus citations -
Discovery and Functional Characterization of a Potent, Selective, and Metabolically Stable PROTAC of the Protein Kinases DYRK1A and DYRK1B
Wilms, G., Schofield, K., Maddern, S., Foley, C., Shaw, Y., Smith, B., Basantes, L. E., Schwandt, K., Babendreyer, A., Chavez, T., McKee, N., Gokhale, V., Kallabis, S., Meissner, F., Rokey, S. N., Dunckley, T., Montfort, W. R., Becker, W. & Hulme, C., Oct 10 2024, In: Journal of Medicinal Chemistry. 67, 19, p. 17259-17289 31 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Link opens in a new tab Scopus citations -
DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner
Strine, M. S., Cai, W. L., Wei, J., Alfajaro, M. M., Filler, R. B., Biering, S. B., Sarnik, S., Chow, R. D., Patil, A., Cervantes, K. S., Collings, C. K., DeWeirdt, P. C., Hanna, R. E., Schofield, K., Hulme, C., Konermann, S., Doench, J. G., Hsu, P. D., Kadoch, C. & Yan, Q. & 1 others, , Jun 2023, In: PLoS biology. 21, 6 June, e3002097.Research output: Contribution to journal › Article › peer-review
Open Access25 Link opens in a new tab Scopus citations
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Expeditious, biologically driven Pilot Libraries for File Enhancement
Hulme, C. (PI)
Project: Research project
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DYRK1A Inhibition as a Novel Treatment Approach for Alzheimer's Disease
Hulme, C. (CoPI) & Hulme, C. (PI)
Project: Research project
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Commercialization of Selective Dyrk1a Inhibitors for Down Syndrome
Hulme, C. (CoPI)
Project: Research project
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Commercialization of Selective Dyrk1a Inhibitors for Down Syndrome
Hulme, C. (CoPI)
Project: Research project
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The Southwest Comprehensive Center for Drug Discovery and Development
Hulme, C. (CoPI)
Project: Research project
Datasets
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CCDC 992449: Experimental Crystal Structure Determination
Ayaz, M. (Creator), Xu, Z. (Creator) & Hulme, C. (Creator), Cambridge Crystallographic Data Centre, 2014
DOI: 10.5517/cc129qhl, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc129qhl&sid=DataCite
Dataset
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CCDC 1052075: Experimental Crystal Structure Determination
Martinez-Ariza, G. (Creator), Ayaz, M. (Creator), Roberts, S. A. (Creator), Rabanal-Leõn, W. A. (Contributor), Arratia-Pérez, R. (Creator) & Hulme, C. (Creator), Cambridge Crystallographic Data Centre, 2015
DOI: 10.5517/cc149rx3, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc149rx3&sid=DataCite
Dataset
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CCDC 916049: Experimental Crystal Structure Determination
Bell, C. E. (Creator), Shaw, A. Y. (Creator), De Moliner, F. (Creator) & Hulme, C. (Creator), Cambridge Crystallographic Data Centre, 2014
DOI: 10.5517/cczr6zw, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cczr6zw&sid=DataCite
Dataset
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CCDC 985092: Experimental Crystal Structure Determination
Martinez-Ariza, G. (Creator), Ayaz, M. (Creator) & Hulme, C. (Creator), Cambridge Crystallographic Data Centre, 2014
DOI: 10.5517/cc12225d, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc12225d&sid=DataCite
Dataset
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CCDC 1027552: Experimental Crystal Structure Determination
Xu, Z. (Creator), Martinez-Ariza, G. (Creator), Cappelli, A. P. (Creator), Roberts, S. A. (Creator) & Hulme, C. (Creator), Cambridge Crystallographic Data Centre, 2015
DOI: 10.5517/cc13h7vp, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc13h7vp&sid=DataCite
Dataset