Pharmacology

Search results

• A prolactin-dependent sexually dimorphic mechanism of migraine chronification

  Ikegami, D. (Creator), Navratilova, E. (Creator), Yue, X. (Creator), Moutal, A. (Creator), Kopruszinski, C. M. (Creator), Khanna, R. (Creator), Patwardhan, A. (Creator), Dodick, D. W. (Creator) & Porreca, F. (Creator), SAGE Journals, 2021

  DOI: 10.25384/sage.c.5617560.v1, https://sage.figshare.com/collections/A_prolactin-dependent_sexually_dimorphic_mechanism_of_migraine_chronification/5617560/1

  Dataset

• Non-SUMOylated CRMP2 decreases NaV1.7 currents via the endocytic proteins Numb, Nedd4-2 and Eps15

  Gomez, K. (Creator), Ran, D. (Contributor), Madura, C. L. (Creator), Moutal, A. (Creator) & Khanna, R. (Creator), figshare, 2021

  DOI: 10.6084/m9.figshare.c.5278129, https://springernature.figshare.com/collections/Non-SUMOylated_CRMP2_decreases_NaV1_7_currents_via_the_endocytic_proteins_Numb_Nedd4-2_and_Eps15/5278129

  Dataset

• Sex-driven modifiers of Alzheimer’s risk: a multi-modality brain imaging study

  Rahman, A. (Creator), Schelbaum, E. (Creator), Hoffman, K. (Creator), Diaz, I. (Creator), Hristov, H. (Creator), Andrews, R. (Creator), Jett, S. (Creator), Jackson, H. (Creator), Lee, A. (Creator), Sarva, H. (Creator), Pahlajani, S. (Creator), Matthews, D. (Creator), Dyke, J. (Creator), Isaacson, R. (Creator), Brinton, R. (Creator) & Mosconi, L. (Creator), Dryad, Jan 21 2021

  DOI: 10.5061/dryad.zgmsbcc6g, https://datadryad.org/stash/dataset/doi:10.5061/dryad.zgmsbcc6g

  Dataset

• CCDC 853232: Experimental Crystal Structure Determination

  Khanolkar, A. D. (Creator), Lu, D. (Creator), Ibrahim, M. (Creator), Thakur, G. A. (Creator), Porreca, F. (Creator), Veerappan, V. (Creator), Tian, X. (Creator), George, C. (Creator), Parrish, D. A. (Creator), Papahatjis, D. P. (Creator) & Makriyannis, A. (Creator), Cambridge Crystallographic Data Centre, 2012

  DOI: 10.5517/ccxmvmz, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccxmvmz&sid=DataCite

  Dataset

• Additional file 8 of Glycosaminoglycan modifications of betaglycan regulate ectodomain shedding to fine-tune TGF-β signaling responses in ovarian cancer

  Kumari, A. (Creator), Altomare, D. (Creator), Ji, H. (Creator), Starr, M. D. (Creator), Arend, R. C. (Creator), Barton, W. (Creator), Phaëton, R. (Contributor), Raulerson, C. (Creator), Nixon, A. B. (Creator), Lancaster, C. L. (Creator), Hempel, N. (Creator), Lee, N. Y. (Creator), Jenkins-Lane, L. M. (Creator), Shtutman, M. S. (Creator) & Whitaker, R. S. (Creator), figshare, 2024

  DOI: 10.6084/m9.figshare.26681170, https://springernature.figshare.com/articles/figure/Additional_file_8_of_Glycosaminoglycan_modifications_of_betaglycan_regulate_ectodomain_shedding_to_fine-tune_TGF-_signaling_responses_in_ovarian_cancer/26681170

  Dataset

• Additional file 3 of Glycosaminoglycan modifications of betaglycan regulate ectodomain shedding to fine-tune TGF-β signaling responses in ovarian cancer

  Hempel, N. (Creator), Lancaster, C. L. (Creator), Ji, H. (Creator), Arend, R. C. (Creator), Nixon, A. B. (Creator), Lee, N. Y. (Creator), Altomare, D. (Creator), Kumari, A. (Creator), Jenkins-Lane, L. M. (Creator), Raulerson, C. (Creator), Phaëton, R. (Contributor), Barton, W. (Creator), Whitaker, R. S. (Creator), Shtutman, M. S. (Creator) & Starr, M. D. (Creator), figshare, 2024

  DOI: 10.6084/m9.figshare.26681155.v1, https://springernature.figshare.com/articles/figure/Additional_file_3_of_Glycosaminoglycan_modifications_of_betaglycan_regulate_ectodomain_shedding_to_fine-tune_TGF-_signaling_responses_in_ovarian_cancer/26681155/1

  Dataset

• Additional file 6 of Glycosaminoglycan modifications of betaglycan regulate ectodomain shedding to fine-tune TGF-β signaling responses in ovarian cancer

  Arend, R. C. (Creator), Hempel, N. (Creator), Nixon, A. B. (Creator), Jenkins-Lane, L. M. (Creator), Lee, N. Y. (Creator), Kumari, A. (Creator), Ji, H. (Creator), Lancaster, C. L. (Creator), Barton, W. (Creator), Raulerson, C. (Creator), Phaëton, R. (Contributor), Starr, M. D. (Creator), Altomare, D. (Creator), Whitaker, R. S. (Creator) & Shtutman, M. S. (Creator), figshare, 2024

  DOI: 10.6084/m9.figshare.26681164.v1, https://springernature.figshare.com/articles/figure/Additional_file_6_of_Glycosaminoglycan_modifications_of_betaglycan_regulate_ectodomain_shedding_to_fine-tune_TGF-_signaling_responses_in_ovarian_cancer/26681164/1

  Dataset

• PAR2 activation in the dura causes acute behavioral responses and priming to glyceryl trinitrate in a mouse migraine model

  Mason, B. N. (Creator), Hassler, S. N. (Creator), DeFea, K. (Creator), Boitano, S. (Creator), Vagner, J. (Creator), Price, T. J. (Creator) & Dussor, G. (Creator), figshare, 2023

  DOI: 10.6084/m9.figshare.c.6606122.v1, https://springernature.figshare.com/collections/PAR2_activation_in_the_dura_causes_acute_behavioral_responses_and_priming_to_glyceryl_trinitrate_in_a_mouse_migraine_model/6606122/1

  Dataset

• Mcl-1 bound to compound 17

  Kump, K. J. (Contributor), Miao, L. (Contributor), Mady, A. S. A. (Contributor), Ansari, N. H. (Contributor), Shrestha, U. K. (Contributor), Yang, Y. (Contributor), Pal, M. (Contributor), Liao, C. (Contributor), Perdih, A. (Contributor), Abulwerdi, F. A. (Contributor), Chinnaswamy, K. (Contributor), Meagher, J. L. (Contributor), Carlson, J. M. (Contributor), Khanna, M. (Contributor), Stuckey, J. A. (Contributor) & Nikolovska-Coleska, Z. (Contributor), Protein Data Bank (PDB), Mar 4 2020

  DOI: 10.2210/pdb6U64/pdb, https://www.wwpdb.org/pdb?id=pdb_00006u64

  Dataset

• Fused in sarcoma silences HIV gene transcription and maintains viral latency through suppressing AFF4 gene activation

  Krasnopolsky, S. (Creator), Marom, L. (Creator), Victor, R. A. (Creator), Kuzmina, A. (Creator), Schwartz, J. C. (Creator), Fujinaga, K. (Contributor) & Taube, R. (Creator), figshare, 2019

  DOI: 10.6084/m9.figshare.c.4555205.v1, https://springernature.figshare.com/collections/Fused_in_sarcoma_silences_HIV_gene_transcription_and_maintains_viral_latency_through_suppressing_AFF4_gene_activation/4555205/1

  Dataset

• MOESM2 of Fused in sarcoma silences HIV gene transcription and maintains viral latency through suppressing AFF4 gene activation

  Krasnopolsky, S. (Creator), Marom, L. (Creator), Victor, R. A. (Creator), Kuzmina, A. (Creator), Schwartz, J. C. (Creator), Fujinaga, K. (Contributor) & Taube, R. (Creator), figshare, 2019

  DOI: 10.6084/m9.figshare.8323985.v1, https://springernature.figshare.com/articles/MOESM2_of_Fused_in_sarcoma_silences_HIV_gene_transcription_and_maintains_viral_latency_through_suppressing_AFF4_gene_activation/8323985/1

  Dataset

• A novel, injury-free rodent model of vulnerability for assessment of acute and preventive therapies reveals temporal contributions of CGRP-receptor activation in migraine-like pain

  Kopruszinski, C. M. (Creator), Navratilova, E. (Creator), Swiokla, J. (Creator), Dodick, D. W. (Creator), Chessell, I. P. (Creator) & Porreca, F. (Creator), SAGE Journals, 2020

  DOI: 10.25384/sage.c.5134864, https://sage.figshare.com/collections/A_novel_injury-free_rodent_model_of_vulnerability_for_assessment_of_acute_and_preventive_therapies_reveals_temporal_contributions_of_CGRP-receptor_activation_in_migraine-like_pain/5134864

  Dataset

• Liquid biopsy, using a novel DNA methylation signature, distinguishes pancreatic adenocarcinoma from benign pancreatic disease

  Vrba, L. (Creator), Futscher, B. W. (Creator), Oshiro, M. (Creator), Watts, G. S. (Creator), Menashi, E. (Creator), Hu, C. (Creator), Hammad, H. (Creator), Pennington, D. R. (Creator), Golconda, U. (Creator), Gavini, H. (Creator), Roe, D. J. (Creator), Shroff, R. T. (Creator) & Nelson, M. A. (Creator), figshare, 2022

  DOI: 10.6084/m9.figshare.c.5855943.v1, https://springernature.figshare.com/collections/Liquid_biopsy_using_a_novel_DNA_methylation_signature_distinguishes_pancreatic_adenocarcinoma_from_benign_pancreatic_disease/5855943/1

  Dataset

• CCDC 124415: Experimental Crystal Structure Determination

  Bertha, C. M. (Creator), Flippen-Anderson, J. L. (Creator), Rothman, R. B. (Creator), Porreca, F. (Creator), Davis, P. (Creator), Xu, H. (Creator), Becketts, K. (Creator), Cha, X.-Y. (Creator) & Rice, K. C. (Creator), Cambridge Crystallographic Data Centre, 1996

  DOI: 10.5517/cc45gd4, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc45gd4&sid=DataCite

  Dataset

• Immortalization of normal human mammary epithelial cells in two steps by direct targeting of senescence barriers does not require gross genomic alterations

  Garbe, J. C. (Creator), Vrba, L. (Creator), Sputova, K. (Creator), Fuchs, L. (Creator), Novak, P. (Creator), Brothman, A. R. (Creator), Jackson, M. (Creator), Chin, K. (Contributor), La Barge, M. A. (Contributor), Watts, G. (Creator), Futscher, B. W. (Creator) & Stampfer, M. R. (Creator), figshare, 2014

  DOI: 10.6084/m9.figshare.1241556, https://figshare.com/articles/Immortalization_of_normal_human_mammary_epithelial_cells_in_two_steps_by_direct_targeting_of_senescence_barriers_does_not_require_gross_genomic_alterations/1241556

  Dataset

• Differential expression of Cdk5-phosphorylated CRMP2 following a spared nerve injury

  Moutal, A. (Creator), Ji, Y. (Contributor), Bellampalli, S. S. (Creator) & Khanna, R. (Creator), figshare, 2020

  DOI: 10.6084/m9.figshare.c.5033786.v1, https://springernature.figshare.com/collections/Differential_expression_of_Cdk5-phosphorylated_CRMP2_following_a_spared_nerve_injury/5033786/1

  Dataset

• Sex-driven modifiers of Alzheimer's risk: a multi-modality brain imaging study

  Rahman, A. (Contributor), Schelbaum, E. (Contributor), Hoffman, K. (Contributor), Diaz, I. (Contributor), Hristov, H. (Contributor), Andrews, R. (Contributor), Jett, S. (Contributor), Jackson, H. (Contributor), Lee, A. (Contributor), Sarva, H. (Contributor), Pahlajani, S. (Contributor), Matthews, D. (Contributor), Dyke, J. (Contributor), Isaacson, R. (Contributor), Brinton, R. (Contributor) & Mosconi, L. (Contributor), ZENODO, Oct 2 2021

  DOI: 10.5061/dryad.zgmsbcc6g, https://zenodo.org/records/4455974

  Dataset

• Additional file 1 of Exploring the neurobiology of the premonitory phase of migraine preclinically – a role for hypothalamic kappa opioid receptors?

  Kopruszinski, C. M. (Creator), Vizin, R. (Creator), Watanabe, M. (Creator), Martinez, A. L. (Creator), de Souza, L. H. M. (Creator), Dodick, D. W. (Creator), Porreca, F. (Creator) & Navratilova, E. (Creator), figshare, 2022

  DOI: 10.6084/m9.figshare.21251708.v1, https://springernature.figshare.com/articles/figure/Additional_file_1_of_Exploring_the_neurobiology_of_the_premonitory_phase_of_migraine_preclinically_a_role_for_hypothalamic_kappa_opioid_receptors_/21251708/1

  Dataset

• Evaluation of green light exposure on headache frequency and quality of life in migraine patients: A preliminary one-way cross-over clinical trial

  Martin, L. F. (Creator), Patwardhan, A. M. (Contributor), Jain, S. V. (Contributor), Salloum, M. M. (Creator), Freeman, J. (Creator), Khanna, R. (Creator), Gannala, P. (Creator), Goel, V. (Creator), Jones-MacFarland, F. N. (Contributor), Killgore, W. D. (Creator), Porreca, F. (Creator) & Ibrahim, M. M. (Contributor), SAGE Journals, 2021

  DOI: 10.25384/sage.c.5289916.v1, https://sage.figshare.com/collections/Evaluation_of_green_light_exposure_on_headache_frequency_and_quality_of_life_in_migraine_patients_A_preliminary_one-way_cross-over_clinical_trial/5289916/1

  Dataset

• CCDC 124416: Experimental Crystal Structure Determination

  Bertha, C. M. (Creator), Flippen-Anderson, J. L. (Creator), Rothman, R. B. (Creator), Porreca, F. (Creator), Davis, P. (Creator), Xu, H. (Creator), Becketts, K. (Creator), Cha, X.-Y. (Creator) & Rice, K. C. (Creator), Cambridge Crystallographic Data Centre, 1996

  DOI: 10.5517/cc45gf5, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc45gf5&sid=DataCite

  Dataset

• Additional file 1 of Non-SUMOylated CRMP2 decreases NaV1.7 currents via the endocytic proteins Numb, Nedd4-2 and Eps15

  Gomez, K. (Creator), Ran, D. (Contributor), Madura, C. L. (Creator), Moutal, A. (Creator) & Khanna, R. (Creator), figshare, 2021

  DOI: 10.6084/m9.figshare.13627069, https://springernature.figshare.com/articles/dataset/Additional_file_1_of_Non-SUMOylated_CRMP2_decreases_NaV1_7_currents_via_the_endocytic_proteins_Numb_Nedd4-2_and_Eps15/13627069

  Dataset

• 5UQC : Crystal structure of mouse CRMP2

  Perez-Miller, S. (Contributor), François-Moutal, L. (Contributor), Khanna, M. (Contributor) & Khanna, R. (Contributor), RCSB-PDB, 2017

  DOI: 10.2210/pdb5uqc/pdb, https://www.rcsb.org/structure/5UQC

  Dataset

• CGRP-dependent and independent mechanisms of acute and persistent post-traumatic headache following mild traumatic brain injury in mice

  Navratilova, E. (Creator), Rau, J. (Creator), Oyarzo, J. (Creator), Tien, J. (Creator), Mackenzie, K. (Creator), Stratton, J. (Creator), Remeniuk, B. (Creator), Schwedt, T. (Creator), Anderson, T. (Creator), Dodick, D. (Creator) & Porreca, F. (Creator), SAGE Journals, 2019

  DOI: 10.25384/sage.c.4677494.v1, https://sage.figshare.com/collections/CGRP-dependent_and_independent_mechanisms_of_acute_and_persistent_post-traumatic_headache_following_mild_traumatic_brain_injury_in_mice/4677494/1

  Dataset

• Differential expression of Cdk5-phosphorylated CRMP2 following a spared nerve injury

  Moutal, A. (Creator), Ji, Y. (Contributor), Bellampalli, S. S. (Creator) & Khanna, R. (Creator), figshare, 2020

  DOI: 10.6084/m9.figshare.c.5033786, https://springernature.figshare.com/collections/Differential_expression_of_Cdk5-phosphorylated_CRMP2_following_a_spared_nerve_injury/5033786

  Dataset

• The crystal structure of anti-apoptotic Mcl-1 protein in complex with 2, 5-substituted benzoic acid inhibitor 21

  Kump, K. J. (Contributor), Miao, L. (Contributor), Mady, A. S. A. (Contributor), Ansari, N. H. (Contributor), Shrestha, U. K. (Contributor), Yang, Y. (Contributor), Pal, M. (Contributor), Liao, C. (Contributor), Perdih, A. (Contributor), Abulwerdi, F. A. (Contributor), Chinnaswamy, K. (Contributor), Meagher, J. L. (Contributor), Carlson, J. M. (Contributor), Khanna, M. (Contributor), Stuckey, J. A. (Contributor) & Nikolovska-Coleska, Z. (Contributor), Protein Data Bank (PDB), Mar 4 2020

  DOI: 10.2210/pdb6U6F/pdb, https://www.wwpdb.org/pdb?id=pdb_00006u6f

  Dataset