Pharmacology and Toxicology

Projects

Grants per year 1978 1996 2000 2002 2010 2014 2021

• 4 Active
• 77 Finished
• 215 Not started

Grants per year

Search results

• Active

  EFFECTS OF HAS 2 ON ENDOCARDIAL CUSHION DEVELOPMENT

  Camenisch, T. D. (PI)

  National Institutes of Health

  7/1/00 → …

  Project: Research project

• ALTERED DNA METHYLATION MEDIATES ARSENIC CARCINOGENICITY

  Klimecki, W. (PI)

  National Institutes of Health

  3/31/96 → …

  Project: Research project

• PC12 CELL DIFFERENTIATION DUE TO PDGF RECEPTOR ACTIVATIO

  Vaillancourt, R. R. (PI)

  National Institutes of Health

  10/15/93 → …

  Project: Research project

• ORGANIC PHASE IMMUNOASSAY FOR CHLORINATED DIBENZODIOXINS

  Cherrington, N. J. (PI) & Bignami, G. S. (PI)

  National Institutes of Health

  6/1/92 → …

  Project: Research project

  • Tert Butylhydroquinone 100%
  • Tert-butylhydroquinone 83%
  • Immunoassay 50%
  • Organic Phase 50%
  • EpRE 50%
• Not started

  Human CYP2A and respiratory tract xenobiotic toxicity

  Ding, X. (PI)

  Project: Research project

• Genome Wide CRISPR Screen for Proteins That Transduce Environmental Exposure Signals to the NRF2 Pathway

  Ooi, A. (PI)

  Project: Research project

• Partial Agonists at Estrogen Receptor alpha for Breast Cancer Therapy

  Thatcher, G. (PI) & Thatcher, G. (PI)

  Project: Research project

• Commercialization of Selective Dyrk1a Inhibitors for Down Syndrome

  Hulme, C. (CoPI)

  Project: Research project

• Vanadium, Calcineurin, and Pulmonary Health

  Chen, Y. (PI)

  Project: Research project

• Development of Dosage Forms &Delivery Systems for Antitumor Agents

  Yalkowsky, S. H. (PI)

  Project: Research project

• Novel transgenic mouse models for human p450 research

  Ding, X. (PI)

  Project: Research project

• IND Enabling Studies for a Novel Mas Receptor Agonist for Treatment of Cognitive Impairment in Patients at Risk for Alzheimer's Disease Related Dementia

  Konhilas, J. P. (CoPI), Mansour, H. (CoPI) & Hay, M. (PI)

  Project: Research project

• A Phospholipid-Derived Nanotherapeutic Platform for Improved Colorectal Cancer Immunochemotherapy

  Lu, J. (PI)

  Project: Research project

• DNA Quadruplex Control of hTERT Transcription: A New Therapy for Taxotere Resistant Prostate Cancer

  Miranti, C. (CoPI) & Hurley, L. (PI)

  Project: Research project

• Nomethiazoles Harnessing GABA and NO mimetic activity for Alzheimer's therapy

  Thatcher, G. (PI)

  Project: Research project

• CYTOCHROME P450 AND OLFACTORY CHEMORECEPTION

  Ding, X. (CoPI)

  Project: Research project

• Human endogenous retrovirus superantigen HERV-K18

  Li, H. (PI)

  Project: Research project

• Genomics

  Futscher, B. W. (PI)

  Project: Research project

• Project 2: Epigenomic Actions of Environmental Arsenicals

  Futscher, B. W. (PI)

  Project: Research project

• Identification and characterization of allosteric inhibitors of Zika protease by targeting the NS2B conformational change

  Li, H. (PI)

  Project: Research project

• The protective role of Nrf2 against arsenic-induced toxicity and carcinogenicity

  Zhang, D. D. (PI)

  Project: Research project

• Glioblastoma multiforme therapy via telomerase reverse transcriptase (hTERT) down-regulation. Molecular chaperones redirect quadruplex folding to reverse the effect of hTERT gene promoter mutations.

  Hurley, L. (PI)

  Project: Research project

• Bixin-based dietary skin photoprotection and suppression of photocarcinogenesis

  Wondrak, G. T. (PI)

  Project: Research project

• Role of CYP2A and Hmox1 in the Diabetogenic Effects of Arsenic in Mine Tailings

  Ding, X. (PI)

  Project: Research project

• PROSTANOID MEDIATED CYOPROTECTION

  Lau, S. (PI)

  Project: Research project

• Mechanisms of Transcriptional Repression by Histone Deac

  Smith, C. L. (PI)

  National Institutes of Health

  Project: Research project

  • Transcriptional Repression 100%
  • Histone Deacetylase Inhibitor (HDACi) 100%
  • Histone Deacetylase 100%
  • Promoter Region 100%
  • Histone 78%

• Potential ApoE Isoform-Specific Detrimental Effects of RXR Agonists in Alzheimer'

  Thatcher, G. (CoPI) & Thatcher, G. (CoPI)

  Project: Research project

• Human CYP2A and respiratory tract xenobiotic toxicity

  Ding, X. (PI)

  Project: Research project

• Development of Dosage Forms &Delivery Systems for Antitumor Agents

  Yalkowsky, S. H. (PI)

  Project: Research project

• Applied Biosystems 4800 MALDI TOF/TOF Mass Spectrometer

  Zhu, H. (PI)

  Project: Research project

• Nomethiazoles harnessing GABA and NO mimetic activity for Alzheimer's therapy

  Thatcher, G. (PI) & Thatcher, G. (PI)

  Project: Research project

• Project 2: TOPK/PRPK as Novel Targets for Skin Cancer Prevention

  Wondrak, G. T. (PI)

  Project: Research project

• Repurposing Clinical ACT Antimalarials for Experimental Melanoma Intervention

  Wondrak, G. T. (CoPI) & Wondrak, G. T. (PI)

  Project: Research project

• RATIONAL DESIGN AND SYNTHESIS OF TELOMERASE INHIBITORS

  Hurley, L. (PI)

  Project: Research project

• Mice with olfactory mucosa-specific Cre gene expression

  Ding, X. (PI)

  Project: Research project

• G-quadruplexes formed in human oncogene promoters and their drug complexes

  Yang, D. (PI)

  Project: Research project

• Novel allosteric activation of nicotinamide rescue

  Thatcher, G. (PI)

  Project: Research project

• RNA Surveillance and Protein Translation in FTD

  Zhu, H. (CoPI)

  Project: Research project

• METABOLISM OF CATECHOL ESTROGENS

  Monks, T. (PI)

  Project: Research project

• Investigation of an anti-cancer phytochemical targeting Nrf2

  Zhang, D. D. (PI)

  Project: Research project

• Discovery and Development of a Selective pan-FLT3-ITD Kinase Inhibitor Clinical Candidate for the Treatment of FLT3-ITD-Driven AML

  Li, H. Y. (PI)

  Project: Research project

• Discovery and Development of a Selective pan-FLT3-ITD Kinase Inhibitor Clinical Candidate for the Treatment of FLT3-ITD-Driven AML

  Li, H. Y. (PI)

  Project: Research project

• Targeted Prevention for Non-Melanoma Skin Cancer

  Chow, H.-H. (PI), Wondrak, G. T. (PI) & Hu, C. (PI)

  Project: Research project

• Redox and Protein Homeostasis in Arsenic Tumorigenicity

  Chapman, E. (CoPI) & Chapman, E. (PI)

  Project: Research project

• Nrf2, autophagy, and arsenic carcinogenesis

  Zhang, D. D. (PI)

  Project: Research project

• Mice with olfactory mucosa-specific Cre gene expression

  Ding, X. (PI)

  Project: Research project

• Development of Dosage Forms & Delivery Systems for Antitumor Agents

  Yalkowsky, S. H. (CoPI)

  Project: Research project

• Development of dual inhibitors targeting the viral main protease and the host cathepsin L as SARS-CoV-2 antivirals

  Wang, J. (CoPI)

  Project: Research project

• Drug Discovery Targeting the Influenza A Virus M2-S31N Proton Channel

  Wang, J. (PI)

  Project: Research project

• METABOLISM AS A FACTOR IN DRUG-INDUCED NEUROTOXICITY

  Monks, T. (PI)

  Project: Research project