Pharmacology and Toxicology

Search results

• Dataset: Machine learning-assisted identification and quantification of hydroxylated metabolites of polychlorinated biphenyls in animal samples

  Zhang, C.-Y. (Creator), Li, X. (Creator), Keil Stietz, K. P. (Creator), Sethi, S. (Creator), Yang, W. (Creator), Marek, R. F. (Creator), Ding, X. (Creator), Lein, P. J. (Creator), Hornbuckle, K. C. (Creator) & Lehmler, H.-J. (Creator), University of Iowa, 2022

  DOI: 10.25820/data.006179, https://iro.uiowa.edu/esploro/outputs/dataset/9984265745002771

  Dataset

• Solution structure of the DNA-hexamer ATGCAT complexed with DNA Bis-intercalating Anticancer Drug XR5944 (MLN944)

  Dai, J. (Contributor), Punchihewa, C. (Contributor), Mistry, P. (Contributor), Ooi, A. T. (Contributor) & Yang, D. (Contributor), Protein Data Bank (PDB), Sep 28 2004

  DOI: 10.2210/pdb1X95/pdb, https://www.wwpdb.org/pdb?id=pdb_00001x95

  Dataset

• Additional file 2 of Formoterol dynamically alters endocannabinoid tone in the periaqueductal gray inducing headache

  Peterson, I. L. (Creator), Liktor-Busa, E. (Creator), Karlage, K. L. (Creator), Young, S. J. (Creator), Scholpa, N. E. (Creator), Schnellmann, R. G. (Creator) & Largent-Milnes, T. M. (Creator), figshare, 2024

  DOI: 10.6084/m9.figshare.27861335.v1, https://springernature.figshare.com/articles/figure/Additional_file_2_of_Formoterol_dynamically_alters_endocannabinoid_tone_in_the_periaqueductal_gray_inducing_headache/27861335/1

  Dataset

• Crystal structure of the NM23-H2 transcription factor complex with dinucleotide d(AG)

  Dexheimer, T. S. (Contributor), Carey, S. S. (Contributor), Zuohe, S. (Contributor), Gokhale, V. M. (Contributor), Hu, X. (Contributor), Murata, L. B. (Contributor), Maes, E. M. (Contributor), Weichsel, A. (Contributor), Sun, D. (Contributor), Meuillet, E. J. (Contributor), Montfort, W. R. (Contributor), Hurley, L. H. (Contributor), Moréra, S. (Contributor), Lacombe, M.-L. (Contributor), Yingwu, X. (Contributor) & Joël Janin, G. L. A. (Contributor), Protein Data Bank (PDB), Sep 23 2008

  DOI: 10.2210/pdb3BBB/pdb, https://www.wwpdb.org/pdb?id=pdb_00003bbb

  Dataset

• The S31N mutant of the influenza A M2 proton channel in two distinct conformational states

  Thomaston, J. L. (Contributor), Wu, Y. (Contributor), Polizzi, N. (Contributor), Liu, L. (Contributor), Wang, J. (Contributor) & Degrado, W. F. (Contributor), Protein Data Bank (PDB), Jun 26 2019

  DOI: 10.2210/pdb6MJH/pdb, https://www.wwpdb.org/pdb?id=pdb_00006mjh

  Dataset

• G-quadruplex structure formed in human Bcl-2 promoter, hybrid form

  Dai, J. (Contributor), Chen, D. (Contributor), Jones, R. A. (Contributor), Hurley, L. H. (Contributor) & Yang, D. (Contributor), Protein Data Bank (PDB), Nov 7 2006

  DOI: 10.2210/pdb2F8U/pdb, https://www.wwpdb.org/pdb?id=pdb_00002f8u

  Dataset

• Human telomere DNA quadruplex structure in K+ solution hybrid-2 form

  Dai, J. (Contributor), Carver, M. (Contributor), Punchihewa, C. (Contributor), Jones, R. A. (Contributor) & Yang, D. (Contributor), Protein Data Bank (PDB), Dec 4 2007

  DOI: 10.2210/pdb2JPZ/pdb, https://www.wwpdb.org/pdb?id=pdb_00002jpz

  Dataset

• Linkage of NAMPT promoter variants to eNAMPT secretion, plasma eNAMPT levels, and ARDS severity

  Garcia, J. G. N. (Creator), Camp, S. M. (Creator), Ramos, N. (Creator), Karnes, J. H. (Creator), Oiţă, R. C. (Contributor), Coletta, D. K. (Creator), Casanova, N. G. (Creator), Bime, C. (Creator), Sun, B. L. (Creator), Lanham, C. (Creator), Sun, X. (Creator), Ellis, N. A. (Creator), Lynn, H. (Creator) & Reyes-Hernon, V. (Contributor), SAGE Journals, 2023

  DOI: 10.25384/sage.c.6754694.v1, https://sage.figshare.com/collections/Linkage_of_NAMPT_promoter_variants_to_eNAMPT_secretion_plasma_eNAMPT_levels_and_ARDS_severity/6754694/1

  Dataset

• G-quadruplex structure formed at the 5'-end of NHEIII_1 element in human c-MYC promoter

  Mathad, R. I. (Contributor), Hatzakis, E. (Contributor), Dai, J. (Contributor) & Yang, D. (Contributor), Protein Data Bank (PDB), Feb 22 2012

  DOI: 10.2210/pdb2LBY/pdb, https://www.wwpdb.org/pdb?id=pdb_00002lby

  Dataset

• Linkage of NAMPT promoter variants to eNAMPT secretion, plasma eNAMPT levels, and ARDS severity

  Bime, C. (Creator), Lanham, C. (Creator), Reyes-Hernon, V. (Contributor), Garcia, J. G. N. (Creator), Camp, S. M. (Creator), Casanova, N. G. (Creator), Ramos, N. (Creator), Lynn, H. (Creator), Coletta, D. K. (Creator), Oiţă, R. C. (Contributor), Sun, X. (Creator), Ellis, N. A. (Creator), Sun, B. L. (Creator) & Karnes, J. H. (Creator), SAGE Journals, 2023

  DOI: 10.25384/sage.c.6754694, https://sage.figshare.com/collections/Linkage_of_NAMPT_promoter_variants_to_eNAMPT_secretion_plasma_eNAMPT_levels_and_ARDS_severity/6754694

  Dataset

• Myosin light chain kinase (MYLK) coding polymorphisms modulate human lung endothelial cell barrier responses via altered tyrosine phosphorylation, spatial localization, and lamellipodial protrusions

  Wang, T. (Creator), Brown, M. E. (Contributor), Kelly, G. T. (Creator), Camp, S. M. (Creator), Mascarenhas, J. B. (Creator), Sun, X. (Creator), Dudek, S. M. (Contributor) & Garcia, J. G. N. (Creator), SAGE Journals, 2018

  DOI: 10.25384/sage.c.4118246.v1, https://sage.figshare.com/collections/Myosin_light_chain_kinase_i_MYLK_i_coding_polymorphisms_modulate_human_lung_endothelial_cell_barrier_responses_via_altered_tyrosine_phosphorylation_spatial_localization_and_lamellipodial_protrusions/4118246/1

  Dataset

• Additional file 4 of Formoterol dynamically alters endocannabinoid tone in the periaqueductal gray inducing headache

  Peterson, I. L. (Creator), Liktor-Busa, E. (Creator), Karlage, K. L. (Creator), Young, S. J. (Creator), Scholpa, N. E. (Creator), Schnellmann, R. G. (Creator) & Largent-Milnes, T. M. (Creator), figshare, 2024

  DOI: 10.6084/m9.figshare.27861344.v1, https://springernature.figshare.com/articles/figure/Additional_file_4_of_Formoterol_dynamically_alters_endocannabinoid_tone_in_the_periaqueductal_gray_inducing_headache/27861344/1

  Dataset

• Additional file 1 of Formoterol dynamically alters endocannabinoid tone in the periaqueductal gray inducing headache

  Peterson, I. L. (Creator), Liktor-Busa, E. (Creator), Karlage, K. L. (Creator), Young, S. J. (Creator), Scholpa, N. E. (Creator), Schnellmann, R. G. (Creator) & Largent-Milnes, T. M. (Creator), figshare, 2024

  DOI: 10.6084/m9.figshare.27861332.v1, https://springernature.figshare.com/articles/figure/Additional_file_1_of_Formoterol_dynamically_alters_endocannabinoid_tone_in_the_periaqueductal_gray_inducing_headache/27861332/1

  Dataset

• Surfing the right ventricular pressure waveform: methods to assess global, systolic and diastolic RV function from a clinical right heart catheterization

  Vanderpool, R. R. (Creator), Puri, R. (Creator), Osorio, A. (Creator), Wickstrom, K. (Creator), Desai, A. A. (Creator), Black, S. M. (Creator), Garcia, J. G. N. (Creator), Yuan, J.X.-J. (Creator) & Rischard, F. P. (Creator), SAGE Journals, 2020

  DOI: 10.25384/sage.c.4864191.v1, https://sage.figshare.com/collections/Surfing_the_right_ventricular_pressure_waveform_methods_to_assess_global_systolic_and_diastolic_RV_function_from_a_clinical_right_heart_catheterization/4864191/1

  Dataset

• NOE-based model of the influenza A virus N31S mutant (19-49) bound to drug 11

  Wu, Y. (Contributor), Canturk, B. (Contributor), Jo, H. (Contributor), Ma, C. (Contributor), Gianti, E. (Contributor), Klein, M. L. (Contributor), Pinto, L. H. (Contributor), Lamb, R. A. (Contributor), Fiorin, G. (Contributor), Wang, J. (Contributor) & Degrado, W. F. (Contributor), Protein Data Bank (PDB), Dec 24 2014

  DOI: 10.2210/pdb2MUW/pdb, https://www.wwpdb.org/pdb?id=pdb_00002muw

  Dataset

• Additional file 5 of Formoterol dynamically alters endocannabinoid tone in the periaqueductal gray inducing headache

  Peterson, I. L. (Creator), Liktor-Busa, E. (Creator), Karlage, K. L. (Creator), Young, S. J. (Creator), Scholpa, N. E. (Creator), Schnellmann, R. G. (Creator) & Largent-Milnes, T. M. (Creator), figshare, 2024

  DOI: 10.6084/m9.figshare.27861347, https://springernature.figshare.com/articles/figure/Additional_file_5_of_Formoterol_dynamically_alters_endocannabinoid_tone_in_the_periaqueductal_gray_inducing_headache/27861347

  Dataset

• Additional file 3 of Formoterol dynamically alters endocannabinoid tone in the periaqueductal gray inducing headache

  Peterson, I. L. (Creator), Liktor-Busa, E. (Creator), Karlage, K. L. (Creator), Young, S. J. (Creator), Scholpa, N. E. (Creator), Schnellmann, R. G. (Creator) & Largent-Milnes, T. M. (Creator), figshare, 2024

  DOI: 10.6084/m9.figshare.27861338, https://springernature.figshare.com/articles/figure/Additional_file_3_of_Formoterol_dynamically_alters_endocannabinoid_tone_in_the_periaqueductal_gray_inducing_headache/27861338

  Dataset

• sj-png-1-tar-10.1177_17534666231181262 – Supplemental material for Linkage of NAMPT promoter variants to eNAMPT secretion, plasma eNAMPT levels, and ARDS severity

  Lynn, H. (Creator), Sun, X. (Creator), Casanova, N. G. (Creator), Bime, C. (Creator), Reyes Hernon, V. (Creator), Lanham, C. (Creator), Oita, R. C. (Creator), Ramos, N. (Creator), Sun, B. (Creator), Coletta, D. K. (Creator), Camp, S. M. (Creator), Karnes, J. H. (Creator), Ellis, N. A. (Creator) & Garcia, J. G. N. (Creator), SAGE Journals, 2023

  DOI: 10.25384/sage.23730593.v1, https://sage.figshare.com/articles/figure/sj-png-1-tar-10_1177_17534666231181262_Supplemental_material_for_Linkage_of_NAMPT_promoter_variants_to_eNAMPT_secretion_plasma_eNAMPT_levels_and_ARDS_severity/23730593/1

  Dataset

• CCDC 2042942: Experimental Crystal Structure Determination

  Shepard, A. J. (Contributor), Townsend, J. A. (Contributor), Foley, C. (Contributor), Hulme, C. (Contributor), Marty, M. T. (Contributor) & Jewett, J. C. (Contributor), Cambridge Crystallographic Data Centre, 2021

  DOI: 10.5517/ccdc.csd.cc26kvc0, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc26kvc0&sid=DataCite

  Dataset

• Linkage of NAMPT promoter variants to eNAMPT secretion, plasma eNAMPT levels, and ARDS severity

  Lynn, H. (Creator), Sun, X. (Creator), Casanova, N. G. (Creator), Bime, C. (Creator), Reyes Hernon, V. (Creator), Oita, R. C. (Creator), Sun, B. (Creator), Coletta, D. K. (Creator), Camp, S. M. (Creator), Karnes, J. H. (Creator) & Garcia, J. G. N. (Creator), SAGE Journals, 2023

  DOI: 10.25384/sage.c.6754694, https://sage.figshare.com/collections/Linkage_of_NAMPT_promoter_variants_to_eNAMPT_secretion_plasma_eNAMPT_levels_and_ARDS_severity/6754694

  Dataset

• CCDC 1039698: Experimental Crystal Structure Determination

  Xu, Z. (Creator), Martinez-Ariza, G. (Creator), Cappelli, A. P. (Creator), Roberts, S. A. (Creator) & Hulme, C. (Creator), Cambridge Crystallographic Data Centre, 2015

  DOI: 10.5517/cc13wwnj, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc13wwnj&sid=DataCite

  Dataset

• CCDC 992449: Experimental Crystal Structure Determination

  Ayaz, M. (Creator), Xu, Z. (Creator) & Hulme, C. (Creator), Cambridge Crystallographic Data Centre, 2014

  DOI: 10.5517/cc129qhl, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc129qhl&sid=DataCite

  Dataset

• Surfing the right ventricular pressure waveform: methods to assess global, systolic and diastolic RV function from a clinical right heart catheterization

  Vanderpool, R. R. (Creator), Puri, R. (Creator), Osorio, A. (Creator), Wickstrom, K. (Creator), Desai, A. A. (Creator), Black, S. M. (Creator), Garcia, J. G. N. (Creator), Yuan, J.X.-J. (Creator) & Rischard, F. P. (Creator), SAGE Journals, 2020

  DOI: 10.25384/sage.c.4864191, https://sage.figshare.com/collections/Surfing_the_right_ventricular_pressure_waveform_methods_to_assess_global_systolic_and_diastolic_RV_function_from_a_clinical_right_heart_catheterization/4864191

  Dataset

• CCDC 992230: Experimental Crystal Structure Determination

  Ayaz, M. (Creator), Xu, Z. (Creator) & Hulme, C. (Creator), Cambridge Crystallographic Data Centre, 2014

  DOI: 10.5517/cc129hf9, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc129hf9&sid=DataCite

  Dataset

• TLR4-NOX2 axis regulates the phagocytosis and killing of Mycobacterium tuberculosis by macrophages

  Lv, J. (Creator), He, X. (Creator), Wang, H. (Creator), Wang, Z. (Creator), Kelly, G. T. (Creator), Wang, X. (Creator), Chen, Y. (Creator), Wang, T. (Creator) & Qian, Z. (Creator), figshare, 2017

  DOI: 10.6084/m9.figshare.c.3952861, https://springernature.figshare.com/collections/TLR4-NOX2_axis_regulates_the_phagocytosis_and_killing_of_Mycobacterium_tuberculosis_by_macrophages/3952861

  Dataset