Asthma/Airway Disease Research Center

2024

Lung-function trajectories: relevance and implementation in clinical practice

CADSET investigators, Apr 13 2024, In: The Lancet. 403, p. 1494-1503 10 p.

Research output: Contribution to journal › Review article › peer-review

2022

Treatment Trials in Young Patients with Chronic Obstructive Pulmonary Disease and Pre–Chronic Obstructive Pulmonary Disease Patients

Martinez, F. J., Agusti, A., Celli, B. R., Han, M. L. K., Allinson, J. P., Bhatt, S. P., Calverley, P., Chotirmall, S. H., Chowdhury, B., Darken, P., da Silva, C. A., Donaldson, G., Dorinsky, P., Dransfield, M., Faner, R., Halpin, D. M., Jones, P., Krishnan, J. A., Locantore, N. & Martinez, F. D. & 10 others, Mullerova, H., Price, D., Rabe, K. F., Reisner, C., Singh, D., Vestbo, J., Vogelmeier, C. F., Wise, R. A., Tal-Singer, R. & Wedzicha, J. A., Feb 1 2022, In: American journal of respiratory and critical care medicine. 205, 3, p. 275-287 13 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

77 Scopus citations

2021

Spirometry: A practical lifespan predictor of global health and chronic respiratory and non-respiratory diseases

Agusti, A., Fabbri, L. M., Baraldi, E., Celli, B., Corradi, M., Faner, R., Martinez, F. D., Melén, E. & Papi, A., Jul 2021, In: European Journal of Internal Medicine. 89, p. 3-9 7 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

24 Scopus citations

2020

Using fractional exhaled nitric oxide to guide step-down treatment decisions in patients with asthma: A systematic review and individual patient data meta-analysis

Wang, K., Verbakel, J. Y., Oke, J., Fleming-Nouri, A., Brewin, J., Roberts, N., Harada, N., Atsuta, R., Takahashi, K., Mori, K., Fujisawa, T., Shirai, T., Kawayama, T., Inoue, H., Lazarus, S., Szefler, S., Martinez, F., Shaw, D., Pavord, I. D. & Thomas, M., 2020, In: European Respiratory Journal. 55, 5, 1902150.

Research output: Contribution to journal › Review article › peer-review

Open Access

25 Scopus citations

2019

Childhood Asthma Inception and Progression: Role of Microbial Exposures, Susceptibility to Viruses and Early Allergic Sensitization

Martinez, F. D., May 2019, In: Immunology and Allergy Clinics of North America. 39, 2, p. 141-150 10 p.

Research output: Contribution to journal › Review article › peer-review

33 Scopus citations

Predicting asthma using clinical indexes

Castro-Rodriguez, J. A., Cifuentes, L. & Martinez, F. D., Jul 1 2019, In: Frontiers in Pediatrics. 7, JULY, 320.

Research output: Contribution to journal › Review article › peer-review

Open Access

41 Scopus citations

2018

After asthma: redefining airways diseases

Pavord, I. D., Beasley, R., Agusti, A., Anderson, G. P., Bel, E., Brusselle, G., Cullinan, P., Custovic, A., Ducharme, F. M., Fahy, J. V., Frey, U., Gibson, P., Heaney, L. G., Holt, P. G., Humbert, M., Lloyd, C. M., Marks, G., Martinez, F. D., Sly, P. D. & von Mutius, E. & 3 others, Wenzel, S., Zar, H. J. & Bush, A., Jan 27 2018, In: The Lancet. 391, 10118, p. 350-400 51 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

763 Scopus citations

Early origins of asthma role of microbial dysbiosis and metabolic dysfunction

Martinez, F. D. & Guerra, S., Mar 1 2018, In: American journal of respiratory and critical care medicine. 197, 5, p. 573-579 7 p.

Research output: Contribution to journal › Review article › peer-review

41 Scopus citations

2017

Focus on asthma in children and adults

Martinez, F. D. & Kraft, M., May 1 2017, In: American journal of respiratory and critical care medicine. 195, 9, p. 1085-1088 4 p.

Research output: Contribution to journal › Review article › peer-review

The long view and the fast lane

Wedzicha, J. A., Brochard, L. J., Martinez, F. D., Martinez, F. J. & Donaldson, G., May 1 2017, In: American journal of respiratory and critical care medicine. 195, 9, p. 1081-1085 5 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

2016

Early-life origins of chronic obstructive pulmonary disease

Martinez, F. D., Sep 1 2016, In: New England Journal of Medicine. 375, 9, p. 871-878 8 p.

Research output: Contribution to journal › Review article › peer-review

367 Scopus citations

2013

Asthma

Martinez, F. D. & Vercelli, D., 2013, In: The Lancet. 382, 9901, p. 1360-1372 13 p.

Research output: Contribution to journal › Review article › peer-review

452 Scopus citations

EAACI position statement on asthma exacerbations and severe asthma

Custovic, A., Johnston, S. L., Pavord, I., Gaga, M., Fabbri, L., Bel, E. H., Le Souëf, P., Lötvall, J., Demoly, P., Akdis, C. A., Ryan, D., Mäkelä, M. J., Martinez, F., Holloway, J. W., Saglani, S., O'Byrne, P., Papi, A., Sergejeva, S., Magnan, A. & Del Giacco, S. & 3 others, Kalayci, O., Hamelmann, E. & Papadopoulos, N. G., Dec 2013, In: Allergy: European Journal of Allergy and Clinical Immunology. 68, 12, p. 1520-1531 12 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

106 Scopus citations

Pooling birth cohorts in allergy and asthma: European union-funded initiatives-a MeDALL, CHICOS, ENRIECO, and GALEN joint paper: CHICOS study group ENRIECO study group GA²LEN study group

ENRIECO Study Group GA, LEN Study Group, MeDALL Study Group & CHICOS Study Group, Jan 1 2013, In: International Archives of Allergy and Immunology. 161, 1, p. 1-10 10 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

53 Scopus citations

2011

MeDALL (Mechanisms of the Development of ALLergy): An integrated approach from phenotypes to systems medicine

Bousquet, J., Anto, J., Auffray, C., Akdis, M., Cambon-Thomsen, A., Keil, T., Haahtela, T., Lambrecht, B. N., Postma, D. S., Sunyer, J., Valenta, R., Akdis, C. A., Annesi-Maesano, I., Arno, A., Bachert, C., Ballester, F., Basagana, X., Baumgartner, U., Bindslev-Jensen, C. & Brunekreef, B. & 49 others, Carlsen, K. H., Chatzi, L., Crameri, R., Eveno, E., Forastiere, F., Garcia-Aymerich, J., Guerra, S., Hammad, H., Heinrich, J., Hirsch, D., Jacquemin, B., Kauffmann, F., Kerkhof, M., Kogevinas, M., Koppelman, G. H., Kowalski, M. L., Lau, S., Lodrup-Carlsen, K. C., Lopez-Botet, M., Lotvall, J., Lupinek, C., Maier, D., Makela, M. J., Martinez, F. D., Mestres, J., Momas, I., Nawijn, M. C., Neubauer, A., Oddie, S., Palkonen, S., Pin, I., Pison, C., Rancé, F., Reitamo, S., Rial-Sebbag, E., Salapatas, M., Siroux, V., Smagghe, D., Torrent, M., Toskala, E., Van Cauwenberge, P., Van Oosterhout, A. J. M., Varraso, R., Von Hertzen, L., Wickman, M., Wijmenga, C., Worm, M., Wright, J. & Zuberbier, T., May 2011, In: Allergy: European Journal of Allergy and Clinical Immunology. 66, 5, p. 596-604 9 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

156 Scopus citations

2010

The role of lipopolysaccharide in the development of atopy in humans: Review

Simpson, A. & Martinez, F. D., Feb 2010, In: Clinical and Experimental Allergy. 40, 2, p. 209-223 15 p.

Research output: Contribution to journal › Review article › peer-review

78 Scopus citations

Which population level environmental factors are associated with asthma, rhinoconjunctivitis and eczema? Review of the ecological analyses of ISAAC Phase One

Innes Asher, M., Stewart, A. W., Mallol, J., Montefort, S., Lai, C. K. W., Aït-Khaled, N., Odhiambo, J., Anabwani, G., Anderson, H. R., Clayton, T. O., Ellwood, P., Mitchell, E. A., Beasley, R., Björkstén, B., Burr, M. L., Crane, J., Keil, U., Martinez, F., Pearce, N. & Robertson, C. F. & 138 others, Shah, J. R., Sibbald, B., Strachan, D. P., von Mutius, E., Weiland, S. K., Williams, H. C., Bezzaoucha, A., Melaku, K., Seyoum, B., Esamai, F. O., Onadeko, B. O., Nelson, H., Chen, Y. Z., Chen, K. H., Zhong, N. S., Bao-Shan, M., Xiao, M. L., Lau, Y. L., Baratawidjaja, K., Nishima, S., Teh, K. H., Yeong, L. W., de Bruyne, J., Quah, B. S., Chum, K. W., Cua-Lim, F., Lee, S. I., Lee, B. W., Hsieh, K. H., Vichyanond, P., Trakultivakorn, M., Masjedi, M. R., al-Momen, J. A., Ramadan, F. M., Al Riyami, B. M. S., Bouayad, Z., Bennis, A., Bhutta, Z. A., Salmun, N., Rosário, N., Stein, R., Bezerra, P. G. M., deFreitas Souza, L., Solé, D., Sanchez, I., Amarales, L., Cortez, E., Calvo, M. A., Soto-Quirós, C., Romieu, I., Cukier, G., Guggiari-Chase, J. A., Chiarella, P., Holgado, D., Sears, M. R., Taylor, B., Persky, V., Redding, G. J., Jeffs, D., Grainger, C. R., Priftanji, A., Riikjärv, M. A., Kajosaari, M., Pekkanen, J., Soininen, L., Koivikko, T. A., Khetsuriani, N., Gamkrelidze, A., Leja, M., Lis, G., Brêborowicz, A., Dumitrascu, D., Khaitov, R. M., Kjellman, N. I., Foucard, T., Aripova, T., Kennedy, D., Landau, L., Peat, J., Bauman, A., Moyes, C., Pattemore, P., Barry, D., Mackay, R., Maheshwari, R. M., Joshi, M. K., Pai, U. A., Raghavan, K., Khatav, V. A., Kumar, L., Jain, K. C., Sukumaran, T. U., Rajajee, S., Somu, N., Chopra, K., Jayaraj, G., Kar, P. K., Hanumante, N. M., Riedler, J., Haidinger, G., Vermeire, P., Charpin, D., Godard, P., Taytard, A., Kopferschmitt, C., Annesi-Maesano, I., Kramer, A., Gratziou, C., Powell, P. V., Bonini, S., Bonci, E., Rusconi, F., Biocca, M., Chetoni, L., Chellini, E., Ronchetti, R., Bisanti, L., Forastiere, F., Renzoni, E., Ciccone, G., Piffer, S., Boner, A., Corbo, G., Borges, F. D., Rosado Pinto, J. E., Nunes, C., Lopesdos Santos, J. M., Clancy, L., Busquets, R. M., Rubio, A. D., Asensio, A. R., García-Marcos, L., Arnedo-Pena, A., Guillén-Grima, F., Morales-Suárez-Varela, M. M., Blanco Quirós, A., Shamssain, M. H. & Strachan, D., Jan 21 2010, In: Respiratory Research. 11, 8.

Research output: Contribution to journal › Review article › peer-review

99 Scopus citations

2009

Managing childhood asthma: Challenge of preventing exacerbations

Martinez, F. D., Mar 2009, In: Pediatrics. 123, SUPPL. 3, p. S146-S150

Research output: Contribution to journal › Review article › peer-review

Open Access

27 Scopus citations

2008

Asthma genetics: From linear to multifactorial approaches

Guerra, S. & Martinez, F. D., 2008, In: Annual review of medicine. 59, p. 327-341 15 p.

Research output: Contribution to journal › Review article › peer-review

52 Scopus citations

Early identification of atopy in the prediction of persistent asthma in children

Sly, P. D., Boner, A. L., Björksten, B., Bush, A., Custovic, A., Eigenmann, P. A., Gern, J. E., Gerritsen, J., Hamelmann, E., Helms, P. J., Lemanske, R. F., Martinez, F., Pedersen, S., Renz, H., Sampson, H., von Mutius, E., Wahn, U. & Holt, P. G., 2008, In: The Lancet. 372, 9643, p. 1100-1106 7 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

306 Scopus citations

2007

Gene-environment interactions in asthma: With apologies to William of Ockham

Martinez, F. D., Jan 2007, In: Proceedings of the American Thoracic Society. 4, 1, p. 26-31 6 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

68 Scopus citations

2006

A brief targeted review of susceptibility factors, environmental exposures, asthma incidence, and recommendations for future asthma incidence research

Yeatts, K., Sly, P., Shore, S., Weiss, S., Martinez, F., Geller, A., Bromberg, P., Enright, P., Koren, H., Weissman, D. & Selgrade, M. J., Apr 2006, In: Environmental health perspectives. 114, 4, p. 634-640 7 p.

Research output: Contribution to journal › Review article › peer-review

74 Scopus citations

Serious adverse events and death associated with treatment using long-acting β-agonists

Martinez, F. D., Oct 2006, In: Clinical Reviews in Allergy and Immunology. 31, 2-3, p. 269-278 10 p.

Research output: Contribution to journal › Review article › peer-review

20 Scopus citations

2005

Gene-environment interactions in asthma and allergies: A new paradigm to understand disease causation

Martinez, F. D., Nov 2005, In: Immunology and Allergy Clinics of North America. 25, 4, p. 709-721 13 p.

Research output: Contribution to journal › Review article › peer-review

54 Scopus citations

Prenatal factors associated with the development of eczema in the first year of life

Kurzius-Spencer, M., Halonen, M., Lohman, I. C., Martinez, F. D. & Wright, A. L., Feb 2005, In: Pediatric Allergy and Immunology. 16, 1, p. 19-26 8 p.

Research output: Contribution to journal › Review article › peer-review

17 Scopus citations

2004

Asthma phenotypes in childhood: Lessons from an epidemiological approach

Stein, R. T. & Martinez, F. D., 2004, In: Paediatric Respiratory Reviews. 5, 2, p. 155-161 7 p.

Research output: Contribution to journal › Review article › peer-review

195 Scopus citations

2003

Tucson Children's Respiratory Study: 1980 to present

Taussig, L. M., Wright, A. L., Holberg, C. J., Halonen, M., Morgan, W. J. & Martinez, F. D., Apr 1 2003, In: Journal of Allergy and Clinical Immunology. 111, 4, p. 661-675 15 p.

Research output: Contribution to journal › Review article › peer-review

556 Scopus citations

2002

CD14: An example of gene by environment interaction in allergic disease

Baldini, M., Vercelli, D. & Martinez, F. D., 2002, In: Allergy: European Journal of Allergy and Clinical Immunology. 57, 3, p. 188-192 5 p.

Research output: Contribution to journal › Review article › peer-review

53 Scopus citations

Development of wheezing disorders and asthma in preschool children

Martinez, F. D., 2002, In: Pediatrics. 109, 2 II, p. 362-367 6 p.

Research output: Contribution to journal › Review article › peer-review

255 Scopus citations

Single nucleotide polymorphisms in innate immunity genes: Abundant variation and potential role in complex human disease

Lazarus, R., Vercelli, D., Palmer, L. J., Klimecki, W. J., Silverman, E. K., Richter, B., Riva, A., Ramoni, M., Martinez, F. D., Weiss, S. T. & Kwiatkowski, D. J., 2002, In: Immunological Reviews. 190, p. 9-25 17 p.

Research output: Contribution to journal › Review article › peer-review