Scholarly Works per year
Scholarly Works per year
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2023
Comparison of Toxicities among Different Bumped Kinase Inhibitor Analogs for Treatment of Cryptosporidiosis
Hulverson, M. A., Choi, R., Schaefer, D. A., Betzer, D. P., McCloskey, M. C., Whitman, G. R., Huang, W., Lee, S., Pranata, A., McLeod, M. D., Marsh, K. C., Kempf, D. J., LeRoy, B. E., Zafiratos, M. T., Bielinski, A. L., Hackman, R. C., Ojo, K. K., Arnold, S. L. M., Barrett, L. K., Tzipori, S., & 3 others, Apr 2023, In: Antimicrobial Agents and Chemotherapy. 67, 4Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
2022
Pharmacokinetics and Pharmacodynamics of Clofazimine for Treatment of Cryptosporidiosis
Zhang, C. X., Love, M. S., McNamara, C. W., Chi, V., Woods, A. K., Joseph, S., Schaefer, D. A., Betzer, D. P., Riggs, M. W., Tam, P. Y. I., Van Voorhis, W. C. & Arnold, S. L. M., Jan 2022, In: Antimicrobial Agents and Chemotherapy. 66, 1, e01560-21.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
2021
One health therapeutics: Target-Based drug development for cryptosporidiosis and other apicomplexa diseases
Van Voorhis, W. C., Hulverson, M. A., Choi, R., Huang, W., Arnold, S. L. M., Schaefer, D. A., Betzer, D. P., Vidadala, R. S. R., Lee, S., Whitman, G. R., Barrett, L. K., Maly, D. J., Riggs, M. W., Fan, E., Kennedy, T. J., Tzipori, S., Doggett, J. S., Winzer, P., Anghel, N., Imhof, D., & 6 others, Jan 2021, In: Veterinary Parasitology. 289, 109336.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
2020
A symbiotic bacterium of shipworms produces a compound with broad spectrum anti-apicomplexan activity
O’Connor, R. M., Nepveux, F. J. V., Abenoja, J., Bowden, G., Reis, P., Beaushaw, J., Bone Relat, R. M., Driskell, I., Gimenez, F., Riggs, M. W., Schaefer, D. A., Schmidt, E. W., Lin, Z., Distel, D. L., Clardy, J., Ramadhar, T. R., Allred, D. R., Fritz, H. M., Rathod, P., Chery, L., & 1 others, May 2020, In: PLoS pathogens. 16, 5, e1008600.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Neonatal mouse gut metabolites influence cryptosporidium parvum infection in intestinal epithelial cells
Vandussen, K. L., Funkhouser-Jones, L. J., Akey, M. E., Schaefer, D. A., Ackman, K., Riggs, M. W., Stappenbeck, T. S. & David Sibley, L., Nov 1 2020, In: mBio. 11, 6, p. 1-16 16 p., e02582-20.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
2018
Modelling Cryptosporidium infection in human small intestinal and lung organoids
Heo, I., Dutta, D., Schaefer, D. A., Iakobachvili, N., Artegiani, B., Sachs, N., Boonekamp, K. E., Bowden, G., Hendrickx, A. P. A., Willems, R. J. L., Peters, P. J., Riggs, M. W., O'Connor, R. & Clevers, H., Jul 1 2018, In: Nature Microbiology. 3, 7, p. 814-823 10 p.Research output: Contribution to journal › Article › peer-review
247 Scopus citations -
2017
5-Aminopyrazole-4-carboxamide-based compounds prevent the growth of Cryptosporidium parvum
Huang, W., Choi, R., Hulverson, M. A., Zhang, Z., McCloskey, M. C., Schaefer, D. A., Whitman, G. R., Barrett, L. K., Vidadala, R. S. R., Riggs, M. W., Maly, D. J., Van Voorhis, W. C., Ojo, K. K. & Fan, E., Aug 2017, In: Antimicrobial Agents and Chemotherapy. 61, 8, e00020.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Advances in bumped kinase inhibitors for human and animal therapy for cryptosporidiosis
Hulverson, M. A., Choi, R., Arnold, S. L. M., Schaefer, D. A., Hemphill, A., McCloskey, M. C., Betzer, D. P., Müller, J., Vidadala, R. S. R., Whitman, G. R., Rivas, K. L., Barrett, L. K., Hackman, R. C., Love, M. S., McNamara, C. W., Shaughnessy, T. K., Kondratiuk, A., Kurnick, M., Banfor, P. N., Lynch, J. J., & 6 others, Oct 2017, In: International Journal for Parasitology. 47, 12, p. 753-763 11 p.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
Bumped-kinase inhibitors for cryptosporidiosis therapy
Hulverson, M. A., Vinayak, S., Choi, R., Schaefer, D. A., Castellanos-Gonzalez, A., Vidadala, R. S. R., Brooks, C. F., Herbert, G. T., Betzer, D. P., Whitman, G. R., Sparks, H. N., Arnold, S. L. M., Rivas, K. L., Barrett, L. K., White, A. C., Maly, D. J., Riggs, M. W., Striepen, B., Van Voorhis, W. C. & Ojo, K. K., Apr 15 2017, In: Journal of Infectious Diseases. 215, 8, p. 1275-1284 10 p.Research output: Contribution to journal › Article › peer-review
Open Access50 Scopus citations -
Experimental acute infection of alpacas with Bovine viral diarrhea virus 1 subgenotype b alters peripheral blood and GALT leukocyte subsets
Topliff, C. L., Alkheraif, A. A., Kuszynski, C. A., Davis, W. C., Steffen, D. J., Schmitz, J. A., Eskridge, K. M., Charleston, B., Henningson, J. N. & Kelling, C. L., Mar 1 2017, In: Journal of Veterinary Diagnostic Investigation. 29, 2, p. 186-192 7 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Extended-spectrum antiprotozoal bumped kinase inhibitors: A review
Van Voorhis, W. C., Doggett, J. S., Parsons, M., Hulverson, M. A., Choi, R., Arnold, S. L. M., Riggs, M. W., Hemphill, A., Howe, D. K., Mealey, R. H., Lau, A. O. T., Merritt, E. A., Maly, D. J., Fan, E. & Ojo, K. K., Sep 2017, In: Experimental parasitology. 180, p. 71-83 13 p.Research output: Contribution to journal › Article › peer-review
Open Access47 Scopus citations -
Necessity of Bumped Kinase Inhibitor Gastrointestinal Exposure in Treating Cryptosporidium Infection
Arnold, S. L. M., Choi, R., Hulverson, M. A., Schaefer, D. A., Vinayak, S., Vidadala, R. S. R., McCloskey, M. C., Whitman, G. R., Huang, W., Barrett, L. K., Ojo, K. K., Fan, E., Maly, D. J., Riggs, M. W., Striepen, B. & Van Voorhis, W. C., Jul 1 2017, In: Journal of Infectious Diseases. 216, 1, p. 55-63 9 p.Research output: Contribution to journal › Article › peer-review
Open Access40 Scopus citations -
2016
Novel bumped kinase inhibitors are safe and effective therapeutics in the calf clinical model for cryptosporidiosis
Schaefer, D. A., Betzer, D. P., Smith, K. D., Millman, Z. G., Michalski, H. C., Menchaca, S. E., Zambriski, J. A., Ojo, K. K., Hulverson, M. A., Arnold, S. L. M., Rivas, K. L., Vidadala, R. S. R., Huang, W., Barrett, L. K., Maly, D. J., Fan, E., Van Voorhis, W. C. & Riggs, M. W., Dec 1 2016, In: Journal of Infectious Diseases. 214, 12, p. 1856-1864 9 p.Research output: Contribution to journal › Article › peer-review
Open Access49 Scopus citations -
2015
The secreted effector protein EspZ is essential for virulence of rabbit enteropathogenic Escherichia coli
Wilbur, J. S., Byrd, W., Ramamurthy, S., Ledvina, H. E., Khirfan, K., Riggs, M. W., Boedeker, E. C., Vedantam, G. & Viswanathan, V. K., 2015, In: Infection and Immunity. 83, 3, p. 1139-1149 11 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
2014
Distribution of lymphoid depletion and viral antigen in alpacas experimentally infected with Bovine viral diarrhea virus 1
Steffen, D. J., Topliff, C. L., Schmitz, J. A., Kammerman, J. R., Henningson, J. N., Eskridge, K. M. & Kelling, C. L., Jan 2014, In: Journal of Veterinary Diagnostic Investigation. 26, 1, p. 35-41 7 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
2013
Cathelicidin-like Helminth Defence Molecules (HDMs): Absence of Cytotoxic, Anti-microbial and Anti-protozoan Activities Imply a Specific Adaptation to Immune Modulation
Thivierge, K., Cotton, S., Schaefer, D. A., Riggs, M. W., To, J., Lund, M. E., Robinson, M. W., Dalton, J. P. & Donnelly, S. M., Jul 2013, In: PLoS neglected tropical diseases. 7, 7, e2307.Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
Suspected cholecalciferol rodenticide toxicosis in avian species at a zoological institution
Swenson, J. & Bradley, G. A., Jun 2013, In: Journal of Avian Medicine and Surgery. 27, 2, p. 136-147 12 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
2012
Antibody fusions reduce onset of experimental Cryptosporidium parvum infection in calves
Imboden, M., Schaefer, D. A., Bremel, R. D., Homan, E. J. & Riggs, M. W., Aug 13 2012, In: Veterinary Parasitology. 188, 1-2, p. 41-47 7 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Phospholipases and cationic peptides inhibit Cryptosporidium parvum sporozoite infectivity by parasiticidal and non-parasiticidal mechanisms
Carryn, S., Schaefer, D. A., Imboden, M., Homan, E. J., Bremel, R. D. & Riggs, M. W., Feb 2012, In: Journal of Parasitology. 98, 1, p. 199-204 6 p.Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
2011
Haemosporidian infection in captive masked bobwhite quail (Colinus virginianus ridgwayi), an endangered subspecies of the northern bobwhite quail
Pacheco, M. A., Escalante, A. A., Garner, M. M., Bradley, G. A. & Aguilar, R. F., Dec 15 2011, In: Veterinary Parasitology. 182, 2-4, p. 113-120 8 p.Research output: Contribution to journal › Article › peer-review
37 Scopus citations -
2010
Antibodies fused to innate immune molecules reduce initiation of Cryptosporidium parvum infection in mice
Imboden, M., Riggs, M. W., Schaefer, D. A., Homan, E. J. & Bremel, R. D., Apr 2010, In: Antimicrobial Agents and Chemotherapy. 54, 4, p. 1385-1392 8 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
2008
Antigenic differences within the Cryptosporidium hominis and Cryptosporidium parvum surface proteins P23 and GP900 defined by monoclonal antibody reactivity
Sturbaum, G. D., Schaefer, D. A., Jost, B. H., Sterling, C. R. & Riggs, M. W., Jun 2008, In: Molecular and Biochemical Parasitology. 159, 2, p. 138-141 4 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
2005
Feline systemic reactive angioendotheliomatosis: Eight cases and literature review
Fuji, R. N., Patton, K. M., Steinbach, T. J., Schulman, F. Y., Bradley, G. A., Brown, T. T., Wilson, E. A. & Summers, B. A., Sep 2005, In: Veterinary pathology. 42, 5, p. 608-617 10 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
2003
Caprine herpesvirus-2 in association with naturally occurring malignant catarrhal fever in captive sika deer (Cervus nippon)
Keel, M. K., Patterson, J. G., Noon, T. H., Bradley, G. A. & Collins, J. K., Mar 2003, In: Journal of Veterinary Diagnostic Investigation. 15, 2, p. 179-183 5 p.Research output: Contribution to journal › Article › peer-review
Open Access51 Scopus citations -
Characterization of a Low Molecular Weight Glycolipid Antigen from Cryptosporidium parvum
Priest, J. W., Mehlert, A., Arrowood, M. J., Riggs, M. W. & Ferguson, M. A. J., Dec 26 2003, In: Journal of Biological Chemistry. 278, 52, p. 52212-52222 11 p.Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
2002
Association of IL-10 expression by mucosal lymphocytes with increased expression of Cryptosporidium parvum epitopes in infected epithelium
Wyatt, C. R., Barrett, W. J., Brackett, E. J., Schaefer, D. A. & Riggs, M. W., 2002, In: Journal of Parasitology. 88, 2, p. 281-286 6 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Efficacy of monoclonal antibodies against defined antigens for passive immunotherapy of chronic gastrointestinal cryptosporidiosis
Riggs, M. W., Schaefer, D. A., Kapil, S. J., Barley-Maloney, L. & Perryman, L. E., 2002, In: Antimicrobial Agents and Chemotherapy. 46, 2, p. 275-282 8 p.Research output: Contribution to journal › Article › peer-review
37 Scopus citations -
Hemorrhagic disease in bighorn sheep in Arizona
Noon, T. H., Wesche, S. L., Cagle, D., Mead, D. G., Bicknell, E. J., Bradley, G. A., Riplog-Peterson, S., Edsall, D. & Reggiardo, C., Jan 2002, In: Journal of wildlife diseases. 38, 1, p. 172-176 5 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Hemorrhagic disease in deer in Arizona
Noon, T. H., Wesche, S. L., Heffelfinger, J., Fuller, A., Bradley, G. A. & Reggiardo, C., Jan 2002, In: Journal of wildlife diseases. 38, 1, p. 177-181 5 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
2001
Characterization of an intestinal epithelial cell receptor recognized by the Cryptosporidium parvum sporozoite ligand CSL
Langer, R. C., Schaefer, D. A. & Riggs, M. W., 2001, In: Infection and Immunity. 69, 3, p. 1661-1670 10 p.Research output: Contribution to journal › Article › peer-review
28 Scopus citations -
Constrictive pericarditis secondary to coccidioides immitis infection in a dog
Shubitz, L. F., Matz, M. E., Noon, T. H., Reggiardo, C. C. & Bradley, G. A., Feb 15 2001, In: Journal of the American Veterinary Medical Association. 218, 4, p. 537-540 4 p.Research output: Contribution to journal › Article › peer-review
40 Scopus citations -
Diversity of Salmonella serotypes in cull (market) dairy cows at slaughter
Galland, J. C., Troutt, H. F., Brewer, R. L., Osburn, B. I., Braun, R. K., Sears, P., Schmitz, J. A., Childers, A. B., Richey, E., Murthy, K., Mather, E. & Gibson, M., Nov 1 2001, In: Journal of the American Veterinary Medical Association. 219, 9, p. 1216-1220 5 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Prevalence of Salmonella spp in cull (market) dairy cows at slaughter
Troutt, H. F., Galland, J. C., Osburn, B. I., Brewer, R. L., Braun, R. K., Schmitz, J. A., Sears, P., Childers, A. B., Richey, E., Mather, E., Gibson, M., Murthy, K. & Hogue, A., Nov 1 2001, In: Journal of the American Veterinary Medical Association. 219, 9, p. 1212-1215 4 p.Research output: Contribution to journal › Article › peer-review
35 Scopus citations -
Targeted disruption of CSL ligand - Host cell receptor interaction in treatment of Cryptosporidium parvum infection
Riggs, M. W., Schaefer, D. A., Kapil, S. J., Barley-Maloney, U., Ferryman, L. E. & McNeil, M. R., 2001, In: Journal of Eukaryotic Microbiology. 48, SUPPL., p. 44S-46SResearch output: Contribution to journal › Article › peer-review
1 Scopus citations -
2000
Characterization and formulation of multiple epitope-specific neutralizing monoclonal antibodies for passive immunization against cryptosporidiosis
Schaefer, D. A., Auerbach-Dixon, B. A. & Riggs, M. W., May 2000, In: Infection and Immunity. 68, 5, p. 2608-2616 9 p.Research output: Contribution to journal › Article › peer-review
35 Scopus citations -
1999
Cryptosporidium parvum apical complex glycoprotein CSL contairσ a sporozoite ligand for intestinal epithelial cells
Langer, R. C. & Riggs, M. W., 1999, In: Infection and Immunity. 67, 10, p. 5282-5291 10 p.Research output: Contribution to journal › Article › peer-review
Open Access43 Scopus citations -
Cryptosporidium parvum sporozoite pellicle antigen recognized by a neutralizing monoclonal antibody is a β-mannosylated glycolipid
Riggs, M. W., McNeil, M. R., Perryman, L. E., Stone, A. L., Scherman, M. S. & O'Connor, R. M., Mar 1999, In: Infection and Immunity. 67, 3, p. 1317-1322 6 p.Research output: Contribution to journal › Article › peer-review
Open Access33 Scopus citations -
Evidence of thymus-independent local and systemic antibody responses to Cryptosporidium parvum infection in nude mice
Adjei, A. A., Jones, J. T., Riggs, M. W. & Enriquez, F. J., Aug 1999, In: Infection and Immunity. 67, 8, p. 3947-3951 5 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
1998
Role of immunoglobulin a monoclonal antibodies against P23 in controlling murine Cryptosporidium parvum infection
Javier Enriquez, F. & Riggs, M. W., 1998, In: Infection and Immunity. 66, 9, p. 4469-4473 5 p.Research output: Contribution to journal › Article › peer-review
60 Scopus citations -
1997
Amebiasis in a dog with gastric ulcers and adenocarcinoma
Steele, K. E., Visvesvera, G. S., Bradley, G. A., Lipscomb, T. P. & Gardiner, C. H., Jan 1997, In: Journal of Veterinary Diagnostic Investigation. 9, 1, p. 91-93 3 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Protective Monoclonal Antibody Defines a Circumsporozoite-Like Glycoprotein Exoantigen of Cryptosporidium parvum Sporozoites and Merozoites
Riggs, M. W., Stone, A. L., Yount, P. A., Langer, R. C., Arrowood, M. J. & Bentley, D. L., Feb 15 1997, In: Journal of Immunology. 158, 4, p. 1787-1795 9 p.Research output: Contribution to journal › Article › peer-review
66 Scopus citations -
Risk factors associated with endemic reproductive deficiencies caused by PRRSV infection
Baysinger, A. K., Dewey, C. E., Straw, B. E., Brumm, M. C., Schmitz, J., Doster, A. & Kelling, C., 1997, In: Journal of Swine Health and Production. 5, 5, p. 179-187 9 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
The effect of PRRSV on reproductive parameters in swine herds
Baysinger, A. K., Dewey, C. E., Straw, B. E., Brumm, M. C., Schmitz, J., Doster, A. & Kelling, C., 1997, In: Journal of Swine Health and Production. 5, 5, p. 173-176 4 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
1996
A cloned gene of Cryptosporidium parvum encodes neutralization-sensitive epitopes
Perryman, L. E., Jasmer, D. P., Riggs, M. W., Bohnet, S. G., McGuire, T. C. & Arrowood, M. J., Oct 1 1996, In: Molecular and Biochemical Parasitology. 80, 2, p. 137-147 11 p.Research output: Contribution to journal › Article › peer-review
85 Scopus citations -
Neutralizing monoclonal antibody protects against Cryptosporidium parvum infection by inhibiting sporozoite attachment and invasion
Langer, R. C. & Riggs, M. W., 1996, In: Journal of Eukaryotic Microbiology. 43, 5, p. 76S-77SResearch output: Contribution to journal › Article › peer-review
13 Scopus citations -
Persistent papillomavirus infection in a cat
Lozano-Alarcón, F., Lewis, T. R., Clark, E. G., Bradley, G. A., Shupe, M. R. & Hargis, A. M., 1996, In: Journal of the American Animal Hospital Association. 32, 5, p. 392-396 5 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Protective monoclonal antibodies define a distinct, conserved epitope on an apical complex exoantigen of Cryptosporidium parvum sporozoites
Riggs, M. W., Yount, P. A., Stone, A. L. & Langer, R. C., 1996, In: Journal of Eukaryotic Microbiology. 43, 5, p. 74S-75SResearch output: Contribution to journal › Article › peer-review
3 Scopus citations -
1995
Neuroaxonal degeneration in sheep grazing Sorghum pastures
Bradley, G. A., Reggiardo, C., Noon, T. H., Bicknell, E. J., Lozano-Alarcon, F., Reed, R. E., Riggs, M. W. & Metcalf, H. C., Apr 1995, In: Journal of Veterinary Diagnostic Investigation. 7, 2, p. 229-236 8 p.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
1994
Bovine antibody against Cryptosporidium parvum elicits a circumsporozoite precipitate-like reaction and has immunotherapeutic effect against persistent cryptosporidiosis in SCID mice
Riggs, M. W., Cama, V. A., Leary, H. L. & Sterling, C. R., 1994, In: Infection and Immunity. 62, 5, p. 1927-1939 13 p.Research output: Contribution to journal › Article › peer-review
54 Scopus citations -
Targeted mutagenesis of the phospholipase D gene results in decreased virulence of Corynebacterium pseudotuberculosis
McNamara, P. J., Bradley, G. A. & Songer, J. G., Jun 1994, In: Molecular Microbiology. 12, 6, p. 921-930 10 p.Research output: Contribution to journal › Article › peer-review
90 Scopus citations