The effect of dietary CLA on mammary tumorigenesis

  • Margaret Flowers (Contributor)
  • Ritu Pandey (Contributor)

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Description

Conjugated linoleic acid (CLA), a class of fatty acids found in beef and dairy products, has been shown to inhibit tumorigenesis in a variety of cancer model systems. Based on previously well-documented anti-tumor activity of CLA in rodent models of breast cancer, a pilot study was initiated to examine the effect of dietary CLA in a well-established transgenic model of breast cancer. Western blots were performed for the detection of AKT, c-Src, ERK1/2, and Cdc24. CLA significantly increased tumor burden (p
Date made available2008
PublisherArrayExpress

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