Structure of drug-resistant V27A mutant of the influenza M2 proton channel bound to spiroadamantyl amine inhibitor

Jessica L. Thomaston (Contributor)
Athina Konstantinidi (Contributor)
Lijun Liu (Contributor)
George Lambrinidis (Contributor)
Jingquan Tan (Contributor)
Martin Caffrey (Contributor)
Jun Wang (Contributor)
William F. DeGrado (Contributor)
Antonios Kolocouris (Contributor)

Dataset

Date made available	Jan 15 2020
Publisher	Protein Data Bank (PDB)

DOI
10.2210/pdb6NV1/pdb

Access Dataset

https://www.wwpdb.org/pdb?id=pdb_00006nv1

1 Article

X-ray Crystal Structures of the Influenza M2 Proton Channel Drug-Resistant V27A Mutant Bound to a Spiro-Adamantyl Amine Inhibitor Reveal the Mechanism of Adamantane Resistance
Thomaston, J. L., Konstantinidi, A., Liu, L., Lambrinidis, G., Tan, J., Caffrey, M., Wang, J., Degrado, W. F. & Kolocouris, A., Feb 4 2020, In: Biochemistry. 59, 4, p. 627-634 8 p.
Research output: Contribution to journal › Article › peer-review

Open Access
31 Scopus citations

Cite this

Thomaston, J. L. (Contributor), Konstantinidi, A. (Contributor), Liu, L. (Contributor), Lambrinidis, G. (Contributor), Tan, J. (Contributor), Caffrey, M. (Contributor), Wang, J. (Contributor), Degrado, W. F. (Contributor), Kolocouris, A. (Contributor) (Jan 15 2020). Structure of drug-resistant V27A mutant of the influenza M2 proton channel bound to spiroadamantyl amine inhibitor. Protein Data Bank (PDB). 10.2210/pdb6NV1/pdb

Structure of drug-resistant V27A mutant of the influenza M2 proton channel bound to spiroadamantyl amine inhibitor

DOI

Access Dataset

Research output

X-ray Crystal Structures of the Influenza M2 Proton Channel Drug-Resistant V27A Mutant Bound to a Spiro-Adamantyl Amine Inhibitor Reveal the Mechanism of Adamantane Resistance

Cite this