Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor UAW248

Michael Dominic Sacco (Contributor)
Chunlong Ma (Contributor)
Panagiotis I. Lagarias (Contributor)
Ang Gao (Contributor)
Julia Alma Townsend (Contributor)
Xiangzhi Meng (Contributor)
Peter Dube (Contributor)
Xiujun Zhang (Contributor)
Yanmei Hu (Contributor)
Naoya Kitamura (Contributor)
Brett Hurst (Contributor)
Bart Tarbet (Contributor)
Michael T Marty (Contributor)
Antonios Kolocouris (Contributor)
Yan Xiang (Contributor)
Yu Chen (Contributor)
Jun Wang (Contributor)

Dataset

Date made available	Jun 17 2020
Publisher	Protein Data Bank (PDB)

DOI
10.2210/pdb6XBI/pdb

Access Dataset

https://www.wwpdb.org/pdb?id=pdb_00006xbi

1 Article

Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M^pro and cathepsin L
Sacco, M. D., Ma, C., Lagarias, P., Gao, A., Townsend, J. A., Meng, X., Dube, P., Zhang, X., Hu, Y., Kitamura, N., Hurst, B., Tarbet, B., Marty, M. T., Kolocouris, A., Xiang, Y., Chen, Y. & Wang, J., Dec 9 2020, In: Science Advances. 6, 50, eabe0751.
Research output: Contribution to journal › Article › peer-review

Open Access
274 Scopus citations

Cite this

Sacco, M. D. (Contributor), Ma, C. (Contributor), Lagarias, P. (Contributor), Gao, A. (Contributor), Townsend, J. A. (Contributor), Meng, X. (Contributor), Dube, P. (Contributor), Zhang, X. (Contributor), Hu, Y. (Contributor), Kitamura, N. (Contributor), Hurst, B. (Contributor), Tarbet, B. (Contributor), Marty, M. T. (Contributor), Kolocouris, A. (Contributor), Xiang, Y. (Contributor), Chen, Y. (Contributor), Wang, J. (Contributor) (Jun 17 2020). Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor UAW248. Protein Data Bank (PDB). 10.2210/pdb6XBI/pdb

Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor UAW248

DOI

Access Dataset

Research output

Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against Mpro and cathepsin L

Cite this

Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M^pro and cathepsin L