Comparison of type 1 conventional dendritic cells pre-cDC1 and CD8+ cDC1 and dendritic cells from bendamustine- or cyclophosphamide-treated mice

Dendritic cells (DCs) harvested from murine spleens to evaluate the effect of treatment with two chemotherapeutic agents: bendamustine and cyclophosphamide. Previous work found that bendamustine treatment results in accumulation of the type 1 conventional DC precursor (pre-cDC1). Pre-cDC1 are an understudied population of murine DCs. This 2x2 study compared the transcriptional profile of bendamustine versus cyclophosphamide and pre-cDC1 versus the mature CD8+ cDC1. For inquiries regarding the contents of this dataset, please contact the Corresponding Author listed in the README.txt file. Administrative inquiries (e.g., removal requests, trouble downloading, etc.) can be directed to [email protected]